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How to Budget for NRGR Services


NIMH issued a Guidance Document for studies that plan to collect biospecimens. This Guidance changes the way that studies must plan to fund biospecimen services, increasing the transparency of costs to NIMH and investigators. All grant applicants must now include a detailed budget for submission to an appropriate biorepository during the life of the grant.

Supporting Documents

Budget Requirements

Although specific sharing requirements will differ depending on study design and proposed sample deliverables, NIMH requires that all studies plan and budget for sample collection materials (kits), shipping, quality control, sample processing, long-term storage, and management of sample distributions for approved requests. If your study needs international shipping, you must investigate whether the shipping carrier will include all relevant foreign taxes and fees in their invoices. If you have questions about the specific biospecimen sharing requirements for your application, email NIMH.genomics.resources@mail.nih.gov. There are different models for sample processing that studies may pursue, depending upon study characteristics:

  1. Full Service at NRGR – most studies will find the best solution for sample processing and long-term sample management is to utilize the NIMH Repository for all services. NRGR can offer study consultation and bundled services to maximize budget efficiency.
  2. Distribution of final sample via NRGR – a subset of studies may qualify to send bulk shipments of externally produced DNA to NRGR for storage and distribution. For this sharing method, the study must:
    1. Share high-density whole genome sequencing data at an NIH-approved database for all subjects
    2. Detail QC procedures and budget to submit in NRGR preferred manner to prevent re-labelling or re-aliquoting errors