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Featured Updates
November 16, 2023
The Controls (CT) Distribution v9.2 was published on 2023-10-01. There are 20323 subjects, 20323 of whom have at least one biosample on record at the repository. UPDATE: Study 182 (PIs: Duan, Penzes; R01MH106575, R21MH102685) released new iPSCs into iPSC Collection 11.3, but used subjects from this collection to create the biosamples. Additional IDs have been added to the alt_id file in CT v9.2: dbgap_ids and nrgr_bio_ids for the iPSC biomaterials. Additionally, dx_nimh values have been added to the collection based on clinical review of study-submitted data.
November 16, 2023
The Induced Pluripotent Stem Cell (iPSC) Distribution v11.3 was published on 2023-10-01. There are 819 subjects, 804 of whom have at least one biosample on record at the repository. There are 472 iPSCs, 568 FCLs, and 8 OEs as of the date of release. In addition to case/control studies, the iPSC collection includes 8 family studies. UPDATE: Study 182 (PIs: Duan, Penzes; R01MH106575, R21MH102685) includes 21 individuals previously released in the SZ and CT collections, 21 of whom have at least one biosample on record at the repository. There are 51 iPSCs.
November 16, 2023
The Netherland Twins Register (NTR) Distribution v9.2 was published on 2023-10-01. There are 11990 subjects, 8540 of whom have at least one biosample on record at the repository. The NTR collection includes 1 family study, which includes families that are large and/or multigenerational. UPDATE: Using a previously released phenotypic data file (_phen), additional age_years values have been added to the main distribution file. (NOTE: values in this field represent the median of 5-year bins defined by the study.) Additional biosamples have been added to the alt_id file using information available in the posted _phen file.
November 16, 2023
The Schizophrenia (SZ) Distribution v20.4 was published on 2023-10-01. There are 54704 subjects, 37768 of whom have at least one biosample on record at the repository. In addition to case/control studies, the Schizophrenia collection includes 16 family studies, one or more of which are large/multigenerational. UPDATE: Study 182 (PIs: Duan, Penzes; R01MH106575, R21MH102685) released new iPSCs into iPSC Collection 11.3, but used subjects from this collection to create biosamples. Additional IDs have been added to the alt_id file in SZ 20.4: dbgap_ids and nrgr_bio_ids for the iPSC biomaterials. Two new subjects were released into Study 29. Additionally, subject_type and consent values were updated for numerous individuals in the collection.
September 13, 2023
NRGR is retiring the requirement to submit an Amendment document to gain access to updated Data Distributions. If you have active access to a collection, and that collection gets updated during your approval period, you will gain automatic access to the most recent distribution version. We still recommend that you review the change notes. If you any questions, please contact our help desk.
April 20, 2023
IPSC versions 10.4 and 11.2 released new iPSCs from 34 subjects already present in the Phelan McDermid Syndrome (PMS) collection, generated by a secondary investigator (Ilyas Singec). Those records are now cross-listed in the iPSC distribution and supplemental files. Detailed information regarding these iPSCs can be found in the Additional Files section on the iPSC download page. In addition to the lines generated by Ilyas Singec, 2 more iPSC samples generated by the original PI for a previously released subject have also been added to the collection release.
April 20, 2023
Phelan McDermid Syndrome (PMS) version 1.6 released new iPSCs from 34 subjects already present in the Phelan McDermid Syndrome (PMS) collection, generated by a secondary investigator (Ilyas Singec). Those records are now cross-listed in the iPSC distribution and supplemental files. Detailed information regarding these iPSCs can be found in the Additional Files section on the iPSC download page. The distribution total is 165 subjects, 134 with DNA available.
February 17, 2023
Attention-Deficit Hyperactivity Disorder 2.0 is available with data from Study 51 (PIs: Todd; 5R01MH071629-02). This update adds 1700 individuals, all with DNA available. The distribution total is 7434 subjects, 6659 with DNA available.