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Alzheimer's Disease 3.4

Distribution 3.4 is available with data from Study 17 (CATIE-AD). Study 17 added 185 subjects bringing the total to 2,682 with 1,596 having DNA. Version 3.4 standardized variables in distribution file.

Standard Data & Documentation

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Distribution Bundle [text or excel]: Standard files across disorders, containing demographic, diagnostic, and pedigree information. Sampled (formerly IBX) sample IDs (nrgr_bio_id) and consent level are also provided. Bundle includes data dictionaries.
Study Descriptions.
Pedigree Drawings.

Additional Data Files

AD0 NIMH AD Genetics Initiative 1,411

Genetic Data

Full Genome Genotyping

AD Dataset 2 292 affected sibling pairs with Alzheimer's Disease, using 237 microsattellite markers
AD Dataset 20 Full Genome Screen, 624 markers, 121 subjects
AD Dataset 5 Full Genome Screen

Targeted Genotyping

AD Dataset 1 A2M and APOE on 437 individuals
AD Dataset 3 A2M and BCHE-K
AD Dataset 4 Chromosome 10 Markers
AD Dataset 6 5 SNPs for APOE on 285 individuals

Clinical Instruments

Other

AD Genetics Initiative code manual
AD Genetics Initiative phenotypic data [text or excel] Includes summary level phenotypic data

Study 17 Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) 185

Clinical Instruments

Other

CATIE-AD Phenotypic Data [text or excel] 53 data files including datapoints for each visit during the CATIE-AD clinical trial. Includes ADAS, ADL, BPRS, demographics, physical exam, and medical history.

AD0 — NIMH AD Genetics Initiative

AD Dataset 2 292 affected sibling pairs with Alzheimer's Disease, using 237 microsattellite markers
AD Dataset 20 Full Genome Screen, 624 markers, 121 subjects
AD Dataset 5 Full Genome Screen

AD0 — NIMH AD Genetics Initiative

AD Dataset 1 A2M and APOE on 437 individuals
AD Dataset 3 A2M and BCHE-K
AD Dataset 4 Chromosome 10 Markers
AD Dataset 6 5 SNPs for APOE on 285 individuals

AD0 — NIMH AD Genetics Initiative

AD Genetics Initiative code manual
AD Genetics Initiative phenotypic data [text or excel] Includes summary level phenotypic data

Study 17 — Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE)

CATIE-AD Phenotypic Data [text or excel] 53 data files including datapoints for each visit during the CATIE-AD clinical trial. Includes ADAS, ADL, BPRS, demographics, physical exam, and medical history.