Research Domain Criteria (RDoC)

Details on the RDoC criteria can be found at the NIMH RDoC site.

NOTE: The distribution refers to a collection of studies organized by disorder or theme (see FAQ).  It is important to note that not all individuals in the distribution have DNA available.

Given the major public health implications of identifying genes responsible for severe neuropsychiatric disorders, the National Institute of Mental Health (NIMH) has funded a Human Genetics Initiative. The goal of this Initiative is to establish a national resource of clinical data and biomaterials that are collected from individuals with autism, schizophrenia, bipolar I disorder, depression, obsessive-compulsive disorder, attention-deficit hyperactivity disorder, and other mental disorders.

Data and biomaterials (cell lines and DNA samples) are available to qualified investigators who study the genetics of brain functions, and may be accessed by following a set of instructions.

Distribution 1.0 April 2017

List of Studies

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes
Study 120 RDoC Constructs: Neural Substrates, Heritability, and Relation to Psychopathology RDoC Zald, Lahey R01MH098098 500 400

In Progress*

No studies found.

Rutgers University Rutgers University USC Information Sciences Institute Washington University in St.Louis National Institute of Mental Health