CN Dataset 1 (500K SNP chip on 1,727 individuals)

Researchers who analyze data and biomaterials from the NIMH Controls Genetics Initiative will use the text specified in the Distribution Agreement to acknowledge the contribution of scientists who collected the data and biomaterials.  Researchers who analyze the genetic analysis data available on this page will use the following additional text to acknowledge, in any and all oral and written presentations, disclosures, and publications, the contribution of scientists who generated the genetic analysis data.

Genotype data were generated at the Center for Genotyping & Analysis at the Broad Institute of Harvard and MIT as part of a multi-institutional collaborative research study (PIs: Pamela Sklar, M.D., Ph.D.; Jordan Smoller, M.D., Sc.D.; Vishwajit Nimgaonkar, M.D., Ph.D.; and Edward Scolnick, M.D.). Control DNA samples were obtained from the NIMH Center for Collaborative Studies from: 1) cord blood samples (Vishwajit Nimgaonkar, M.D., Ph.D.) and 2) psychiatrically screened samples (PI: Pablo Gejman, M.D., Ph.D. and collaborators).

Genotyping was performed at the Center for Genotyping and Analysis of the Broad Institute on samples selected from controls available in the NIMH Control Distributions 3.0 and 4.0. Genotypes were obtained as part of a Genome-wide Association Study of Bipolar Disorder.

Genotyping was performed using the Affymetrix GeneChip Human 500K Mapping Array Set according to the manufacturers recommendations.

Raw .CEL files are available for all samples genotyped using the Affymetrix GeneChip Human 500K Mapping Array Set. Contact Bill Howells at to obtain file.

The data are available in a WINZIP compressed file.

21APR2011: (dbSNP tech support) The Affy 500K Array is based on dbSNP build 125 from hg17 (NCBI 35.1).

Rutgers University Rutgers University USC Information Sciences Institute Washington University in St.Louis National Institute of Mental Health