NRGR Studies by Distribution

Distribution Studies Total Target Sample Size
ADHD 5 4954
Alzheimer's Disease 2 2152
Anorexia Nervosa 5 4485
Autism 43 23478
Bipolar Disorder 19 31680
Brain Function 6 7500
Controls 9 44808
Depression 17 37887
iPSC 24 1677
Netherlands Twin Register 1 8540
OCD 9 11349
Phelan-McDermid Syndrome 1 150
RDoC 7 6745
Schizophrenia 37 69424
Fear and Anxiety 2 1170
Suicide 2 6200
Tourette Syndrome 1 1548
22q11.2 Deletion Syndrome 4 1390
Psychosis 3 1710
PTSD 1 154

ADHD

ADHD Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 25 International Multi-Center ADHD Genetics Project (IMAGE) ADHD Faraone, Ebstein, Oades, Roeyer, Asherson, Steinhausen, Rothenberger, Gill, Buitelaar, Miranda R01MH062873 19, 90-99 4954

2694 in dbGaP GAIN

Released in ADHD Dist. 1.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 28 A study of ADHD (CHOP) ADHD Elia 5K23MH066275-05 130

08feb2017: Study 28 (Elias: CHOP) GWAS was one of four sites analyzed by PGC in their 2010 metaanalysis of ADHD, see publication below.  Data will also be available on the NRGR website with ids linked to NRGR cell lines; ids in the current PGC download are not directly linked to NRGR ids.  

pubmed link to PGC ADHD meta-analysis: 

https://www.ncbi.nlm.nih.gov/pubmed/20732625

Data processing - final stages
Study 43 A study of ADHD ADHD Todorov, Todd (deceased) 132 Due, in process, send id list to PI
Study 45 Detection of Susceptibility Genes in ADHD ADHD Sandra Loo (new PI) 5R01MH058277-10 135 Data processing - final stages
Study 51 A study of ADHD ADHD Todorov, Todd (deceased) 121 Due, in process

*Studies in progress includes those available for download for which some future action is required

Alzheimer's Disease

Alzheimer's Disease Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
AD 0 Genetic Studies of Alzheimer's Disease Alzheimer's Disease Albert, Bassett, Go 5U01MH046281, 5U01MH046290, 5U01MH046373 50-52 1411 Released in AD Dist. 1.0
Study 17 CATIE; Replication of Schizophrenia Associations in CATIE Alzheimer's Disease Lieberman, Sullivan N01MH090001, R01MH074027 Site 75-AD; Site 76-SZ 741

741 in NIMH SZ DS 13 (CATIE);291 in NIMH SZ 27;

Site 76 (SZ) released; Site 75 (AD) released in AD Dist. 3.0

In Progress*

No studies found.

Anorexia Nervosa

Anorexia Nervosa Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 24 Genetics of Anorexia Nervosa Anorexia Nervosa Kaye, Fichter, Brandt, Jones, Mitchell, Berrettini, Johnson, Strober, Halmi, Kaplan, Devlin R01MH066122 110-120 1205 Released in ANX Dist. 1.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 96 Olanzapine Versus Placebo in Outpatients with Anorexia Nervosa Anorexia Nervosa Attia, Steinglass, Guarda, Marcus, Kaplan R01MH085921 395-399 160 Data will be deposited within 3 months from end of data preparation
Study 98 The Effects of Estradiol on Genetic Risk for Disordered Eating during Puberty Anorexia Nervosa Klump R01MH092377 246 700 Data received 2014-03-06, updates needed; 6 mos. after last subject's sample has been received by repository
Study 129 Anorexia Nervosa Genetics Initiative (ANGI Project) Anorexia Nervosa Bulik (UNC), Martin (Australian site) Note: Australian site will send samples in 2 batches (at the end of years 2 and 4) Anorexia Nervosa Genetics Initiative (ANGI Project) 403-404 2000 Will be released 6 mos. after last subject's sample has been received by repository
Study 133 Biomarker Discovery in Anorexia Nervosa II Anorexia Nervosa Bulik, Bardone-Cone R01MH095860 405 420 Due 12 mos. after last subject's sample has been received by repository

*Studies in progress includes those available for download for which some future action is required

Autism

Autism Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 4 Collaborative Linkage Study of Autism Autism Folstein (retired), Piven, Sutcliffe R01MH055135 60-61, 89 665

26 in exome seq dbGap ARRA; 12 in dbGaP AGP; 515 in NIMH AU DS3; 12 in dbGaP phs000436;

Released
Study 10 Collaborative Linkage Study in Autism Autism Folstein R01MH055135 62 4

4 in NIMH AU DS3;

Released
Study 14 Molecular Genetics of Infantile Autism Autism Myers R01MH052708 63 563

334 in NIMH AU DS3;

49 in dbGaP ARRA;

Released
Study 21 AGRE; A Genomewide Search for Autism Susceptibility Loci Autism Geschwind R01MH064547 72, 74 3908

442 in exome seq dbGap ARRA; 96 in dbGaP AGP; 16 in dbGap phs000639; 362 in NIMH AU DS3;

Released in AU Dist. 7.0
Study 30 A study of Autism Autism Rodier 158 50 Released in AU Dist. 5.0
Study 31 A study of Autism Autism Rodier 151 79 Released in AU Dist. 5.0
Study 32 A study of Autism Autism Szatmari 152 483

31 in exome seq dbGap ARRA;8 in dbGaP AGP;

Released in AU Dist. 5.0
Study 33 Longitudinal Study of Language and Theory of Mind in Autism Autism Tager-Flusberg P01DC003610 153 210

17 in NIMH AU DS3;

Released in AU Dist. 5.0
Study 34 Neurobiology and Genetics of Autism Autism Dawson U19HD035465 154 214

10 in dbGaP ARRA;

Released in AU Dist. 5.0
Study 35 Molecular and Genetic Epidemiology of Autism Autism Pericak-Vance R01MH080647 155 1220 Released in AU Dist. 8.0
Study 36 A study of Autism Autism McInnis 156 310

4 in exome seq dbGap ARRA;

Released in AU Dist. 5.0
Study 37 RUPP-PI Autism McDougle U10MH066766 157 133

27 in exome seq dbGap ARRA;

Released in AU Dist. 5.0
Study 39 A study of Autism Autism Brzustowicz RC1MH088288 161 Released in AU Dist. 13.0
Study 41 The Development of the Siblings of Children with Autism: A Longitudinal Study Autism King, Hollander, Sigman, Piven, Volkmar, Tager-Flusberg, Hollander P50HD055784 700-707 438

7 in exome seq dbGap ARRA;

Site 702 still collecting samples, project end date is 31-MAY-2017; Sites 700-705, 707 were released in AU Dist 6.0
Study 44 Genetic Analysis of 15q11-q13 in Autism Autism Sutcliffe R01MH061009 165

 134 in dbGaP AGP; 71 in dbGaP phs000436;

Released in AU Dist. 12.0
Study 46 DM-STAT (data coordinating site for Studies 30, 31, 33, 34 & 41) Autism Dagher Released in AU Dist. 5.0 and 6.0
Study 50 Genetics of Autism Intermediate Phenotypes Autism Coon, Hepburn R01MH069359 200-201 1711

129 in exome seq dbGap ARRA;

Released in AU Dist. 9.0
Study 56 Clinical and Immunological Investigations of Subtypes of Autism Autism Swedo, Thurm, Amaral Clinical and Immunological Investigations of Subtypes of Autism 163, 208 Released in AU Dist. 14.0
Study 60 A study of Autism Autism Piven 167 275 Released in AU Dist. 14.0
Study 63 Interdisciplinary Studies of Insistence on Sameness in Autism Spectrum Disorders Autism Cook P50HD055751 168 250

438 in exome seq dbGap UIC ACE;

Released in AU Dist. 13.0
Study 64 Center for Genomic and Phenomic Studies in Autism Autism Lajonchere, Amaral, Constantino, Roullet, Malow, Sohl, Manning, Murray 5U24MH081810 202-207, 229 1263

1 in exome seq dbGap ARRA;

Data processing - initial stages; Site 202 Released; Sites 203-207, 229 not released yet
Study 65 Trio Autism Simplex Collection (TASC) Autism Geschwind, Szatmari, Cook, Dawson, Poustka, Gallagher, Cuccaro, Vicente, McMahon, Sutcliffe, Buxbaum, Nurnberger Funded by Autism Speaks 210-221 3374

1012 in exome seq dbGap ARRA; 1815 in dbGaP AGP;

Released in AU Dist. 10.0
Study 69 Biological and Information Processing Mechanisms Underlying Autism Autism Minshew P50HD055748 209 Released in AU Dist. 13.0
Study 79 Genotypic and Phenotypic Factors in Autism Spectrum Disorders Autism Davis, Demmer, Caronna, Kunkel, Walsh, Frazier R01MH085143, R01MH083565 222-227 1048

(lingwei note): 411 in exome seq dbGap ARRA;

29JUL2016(wbh): genomic data at NDAR under collection 2029, not for transfer to NRGR, target sequence data stays at NDAR, exome sequence goes to dbgap, according to David Obenshain of NDAR who cites agreement with Walsh lab; no gwas dataset

https://ndar.nih.gov/edit_collection.html?id=2029

 

NDAR Primary Deposit, study continued; first batch Released in AU Dist. 11.0
Study 86 Autism-Spectrum Disorder Genetics Autism Haines Autism-Spectrum Disorder Genetics 230 1500 Released in AU Dist. 14.0
Study 112 The Genetics of Autism: Epilepsy as a Biomarker Autism Devinsky (724-725), Schultz (740) The Genetics of Autism: Epilepsy as a Biomarker 724-725, 740 1200 Released in AU Dist. 14.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 41 The Development of the Siblings of Children with Autism: A Longitudinal Study Autism King, Hollander, Sigman, Piven, Volkmar, Tager-Flusberg, Hollander P50HD055784 700-707 438

7 in exome seq dbGap ARRA;

Site 702 still collecting samples, project end date is 31-MAY-2017; Sites 700-705, 707 were released in AU Dist 6.0
Study 64 Center for Genomic and Phenomic Studies in Autism Autism Lajonchere, Amaral, Constantino, Roullet, Malow, Sohl, Manning, Murray 5U24MH081810 202-207, 229 1263

1 in exome seq dbGap ARRA;

Data processing - initial stages; Site 202 Released; Sites 203-207, 229 not released yet
Study 65 Trio Autism Simplex Collection (TASC) Autism Geschwind, Szatmari, Cook, Dawson, Poustka, Gallagher, Cuccaro, Vicente, McMahon, Sutcliffe, Buxbaum, Nurnberger Funded by Autism Speaks 210-221 3374

1012 in exome seq dbGap ARRA; 1815 in dbGaP AGP;

Released in AU Dist. 10.0
Study 79 Genotypic and Phenotypic Factors in Autism Spectrum Disorders Autism Davis, Demmer, Caronna, Kunkel, Walsh, Frazier R01MH085143, R01MH083565 222-227 1048

(lingwei note): 411 in exome seq dbGap ARRA;

29JUL2016(wbh): genomic data at NDAR under collection 2029, not for transfer to NRGR, target sequence data stays at NDAR, exome sequence goes to dbgap, according to David Obenshain of NDAR who cites agreement with Walsh lab; no gwas dataset

https://ndar.nih.gov/edit_collection.html?id=2029

 

NDAR Primary Deposit, study continued; first batch Released in AU Dist. 11.0
Study 89 Identification of Characteristics Associated with Symptom Remission in Autism Autism Black Identification of Characteristics Associated with Symptom Remission in Autism 231 180 5th RFD email sent 11/7/2016; Due 8/1/2013
Study 95 Abnormal Sterols in ASD and NIMH HGI Repository Expansion (4000) Autism Tierney, Porter, Arnold RC2MH090027 232-234 400 7th RFD email sent 2/8/2017; Due 11/30/2013
Study 97 Studies of Autistic Patients: Gene Networks and Clinical Subtypes Autism Rennert, Swedo, Thurm, Raygado Studies of Autistic Patients: Gene Networks and Clinical Subtypes 235 300 7th RFD email sent 2/8/2017; Due 12/31/2013
Study 100 A Longitudinal Imaging Study of Infants at Risk for Autism Autism Piven, Schultz, Botteron, Dagar R01HD055741 236-239 700 NDAR primary deposit; Data will be submitted to NDAR around December 2016
Study 118 Next Generation Gene Discovery in Familial Autism Autism Brkanac R01MH092367 729 60 NDAR primary deposit: requesting access
Study 126 Autism (ACE Network) Autism Constantino, Klin, Molholm R01MH100027 712, 718-720 600 NDAR Primary Deposit; Will be released 6 mos. after last subject's sample has been received by repository
Study 128 A Comprehensive Approach To Identification of Autism Susceptibility Genes Autism Lajonchere, Schultz, Johnson, Reynolds, Butter R01MH081754 713-716 196 NDAR primary deposit: requesting access; Will be released 6 mos. after last subject's sample has been received by repository
Study 135 Multimodal Developmental Neurogenetics of Females with ASD Autism Pelphrey, Nelson, Bookheimer, Webb R01MH100028 470-473 312 Will be released 6 mos. after last subject's sample has been received by repository
Study 146 Induced Neuronal Cells: A Novel Approach to Study Neuropsychiatric Diseases Autism Wernig/Südhof R01MH092931 741 12 6th RFD email sent 2/8/2017; Released no later than 10/31/2015
Study 164 The Autism Biomarkers Consortium for Clinical Trials (ABC-CT) Autism McPartland, Charwarska, Nelson, Dawson, Jeste, Bernier 1U19MH108206-01 474-478 200 Will be released 3 mos. after the end of the project period, 9/30/2019
Study 172 A Clinical Study to Establish a Metabolic Biomarker-Based Test to Diagnose Autism Spectrum Disorder in Early Childhood Autism Robert Burrier (PI), David Amaral, Daniel Coury, Melmed Raun, Kevin Sanders, Richard Frye, Logan Wink, Ann Neumeyer 1R44MH107124-01 772-777, 784, 786 1500 Will be released to the public no later than 1/31/2019
Study 175 Neurobiology of Autism with Macrocephaly Autism Flora Vaccarino R01MH109648 780 120 Will be released to the public no later than 10/30/2021

*Studies in progress includes those available for download for which some future action is required

Bipolar Disorder

Bipolar Disorder Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
BP 0 Linkage Studies of Bipolar Disorder Bipolar Disorder Nurnberger, Reich, DePaulo, Gershon 5U01MH046282, 5U01MH046280, 5U01MH046274 10-13 1353

175 in dbGaP BP GAIN; 112 in NIMH BP-DS11 phase1; 174 in NIMH BP-DS11 phase2;

Released in BP Dist. 1.0
Study 1 A Collaborative Genomic Study of Bipolar Disorder Bipolar Disorder Berrettini, Byerley, Coryell, DePaulo, Gershon, Kelsoe, Nurnberger, Reich, Sheftner, Murphy R01MH059545 20-29 1768

387 in dbGaP BP GAIN;  280 in NIMH BP DS11 phase1; 429 in NIMH BP DS11 phase2;

Released
Study 2 Molecular Genetics of Bipolar Disorder Bipolar Disorder Baron R01MH059602 Site 15-US; Site 16-Israel 843

72 in GWAS Pritzker 1, 94 in GWAS Pritzker 2

Released
Study 8 Genetic Analysis of Bipolar Disorder Bipolar Disorder Pato R01MH058693 38 223 Released
Study 19 STEP-BD; Treatment of Bipolar Disorder Bipolar Disorder Sachs, Nimgaonkar N01MH080001 14, 78, 86, Site 88-Controls 2365

847 cases and 453 ctls in STEP-BD GWAS; 486 in NIMH Controls DS 1;  105 in dbGap NIMH-CTL Exome;

Released in BP Dist. 6.0 (Site 78)/Controls Dist. 6.0 (Site 88); Sites 14 & 86 not released yet
Study 40 Bipolar Genome Study (BiGS) Bipolar Disorder Schetner, Gershon, McMahon, Kelsoe, Nurnberger, McInnis, Berrettini, Byerley, Coryell, Lawson, Rice, Univ. of Michigan P50CA89392 from the National Cancer Institute; K02DA021237 from the National Institute of Drug Abuse 170-181 3934

853 in dbGaP BP GAIN

Released in BP Dist. 5.0
Study 49 Genetics of Bipolar Disorder in Latino Populations Bipolar Disorder Escamilla, Medoza, Paso, Paez, Jerez, Raventos, Nicolini, Ontiveros R01MH069856 190-197 2688 Released in BP Dist. 7.0
Study 55 Adolescents at High Risk for Familial Bipolar Disorder Bipolar Disorder Nurnberger, Kastelli, McInnis, Reich R01MH068009 750-753 374 Released in BP Dist. 8.0
Study 71 Bipolar Endophenotypes in Population Isolates Bipolar Disorder Freimer, Macaya, Ospina-Duque R01MH075007 198-199 560 Released in BP Dist. 9.0
Study 75 Lithium Use for Bipolar Disorder: A Randomized Controlled Effectiveness Trial (LiTMUS) Bipolar Disorder Nierenberg, Ostacher,Iosifescu, Thase, Ketter, Bowden, Calabrese, Friedman Lithium Use for Bipolar Disorder: A Randomized Controlled Effectiveness Trial 189 193 Released in BP Dist. 11.0
Study 77 International Cohort Collection for Bipolar Disorder Bipolar Disorder Smoller, Sklar, Pato, Knowles, Bromet, Rapaport, Buckley, Escamilla, Morley, Dewan, Lehrer, Marder, Perkins, Malaspina, Nicolini R01MH085542 252, 270, 272-275, 304-312 8947 Updated data received 2016-12-02, in processing; Part 1 released in BP Dist. 10.0 and Controls Dist. 8.0
Study 123 Acute Psychotherapy for Bipolar II Depression Bipolar Disorder Swartz R01MH084831 432 38 Released in BP Dist. 10.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 19 STEP-BD; Treatment of Bipolar Disorder Bipolar Disorder Sachs, Nimgaonkar N01MH080001 14, 78, 86, Site 88-Controls 2365

847 cases and 453 ctls in STEP-BD GWAS; 486 in NIMH Controls DS 1;  105 in dbGap NIMH-CTL Exome;

Released in BP Dist. 6.0 (Site 78)/Controls Dist. 6.0 (Site 88); Sites 14 & 86 not released yet
Study 48 A study of Bipolar Disorder Bipolar Disorder McMahon, DePaulo, Gershon 186-188 642 Data received 2012; updated data received Sept 2016; still need fix pedigree
Study 77 International Cohort Collection for Bipolar Disorder Bipolar Disorder Smoller, Sklar, Pato, Knowles, Bromet, Rapaport, Buckley, Escamilla, Morley, Dewan, Lehrer, Marder, Perkins, Malaspina, Nicolini R01MH085542 252, 270, 272-275, 304-312 8947 Updated data received 2016-12-02, in processing; Part 1 released in BP Dist. 10.0 and Controls Dist. 8.0
Study 101 Pharmacogenomics of Mood Stabilizer Response in Bipolar Disorder Bipolar Disorder Kelsoe, Nievergelt, Calabrese, Nurnberger, McInnis, Gershon, Potash, Zandi, Berrettini, Lohoff, Coryell, Alda, Odegaard U01MH092758 420-429 700 using auto-QC email was sent 2016-3-2; RFD 6/10/2016;
Study 102 Genomic Studies of Bipolar Disorder in a Large Cohort from the Netherlands Bipolar Disorder Ophoff, Daalman R01MH090553 430-431 2500 7th RFD email sent 2/8/2017; Due 3/31/2015
Study 140 Genome Sequencing in Extended Bipolar Pedigrees Bipolar Disorder Fremier, Jaramillo, Macaya 3R01MH095454-02S1 435-436 2000 7th RFD email sent 2/8/2017; Using auto-QC email was send 3/9/2016; Will be released 6 mos. after last subject's sample has been received by repository but no later than 11/30/2015
Study 156 Transferred from Coriell Collection Bipolar Disorder DeLisi, Gershon Site 735 (BP); Site 736 (SZ) 2500 Data received, waiting on PI resolve issues, 2016-3-2 contacted with excel files, 2016-5-23 send follow-up emails
Study 179 Ultra High Field Strength MRI and MRS Study of Bipolar Disorder in Adolescents Bipolar Disorder Hilary Patricia Blumberg 1R21MH108940-01A1 789 52 Will be released to the public no later than 12/30/2018

*Studies in progress includes those available for download for which some future action is required

Brain Function

Brain Function Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 109 Discovery Science of Human Brain Function Across the Lifespan Brain Function Milham R01MH094639 303 1000 Released in Brain Function Dist. 1.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 58 Genetics of Brain Structure and Function Brain Function Blangero, Glahn R01MH078111, R01MH078143 136 1300 Received data Aug 7,2015, updates Aug 19,2015, still need family id
Study 114 Mapping the Human Connectome: Structure, Function, and Heritability Brain Function Van Essen U54MH091657 400 1800 7th RFD email sent 2/8/2017; Will be released 6 mos. after last subject's sample has been received by repository
Study 168 Mapping the Human Connectome During Typical Aging Brain Function David Van Essen, Melissa Terpstra, Susan Bookheimer, David Salat 1U01AG052564 797-800 1500 Will be released to the public no later than 11/30/2020
Study 178 Human Connectome Project for Early Psychosis Brain Function Martha Elizabeth Shenton, Alan Breier U01MH109977 791-792 400 Will be released to the public no later than 8/29/2020
Study 180 Mapping the Human Connectome During Typical Development Brain Function David Van Essen, Deanna Barch, Leah Somerville, Susan Bookheimer, Kathleen Thomas 1U01MH109589 1500 Will be released to the public no later than 10/30/2020

*Studies in progress includes those available for download for which some future action is required

Controls

Controls Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 19 STEP-BD; Treatment of Bipolar Disorder Controls Sachs, Nimgaonkar N01MH080001 14, 78, 86, Site 88-Controls 2365

847 cases and 453 ctls in STEP-BD GWAS; 486 in NIMH Controls DS 1;  105 in dbGap NIMH-CTL Exome;

Released in BP Dist. 6.0 (Site 78)/Controls Dist. 6.0 (Site 88); Sites 14 & 86 not released yet
Study 23 Genetic Susceptibility in Schizophrenia Controls Nimgaonkar R01MH056242 73 489 Released in SZ Dist. 8.0 and Controls Dist
Study 29 Molecular Genetics of Schizophrenia Controls Gejman, Levinson, Buccola, Mowry, Freedman, Amin, Byerley, Crowe, Silverman, Cloninger R01MH059571 139-150 8989

 

1212 in NIMH Controls DS 1
463 in NIMH DS 2
1705 in dbGaP BP GAIN
1033 in STEP-BD GWAS
461 in GWAS Pritzker 1
311 in GWAS Pritzker 2
2142 cases and 2332 ctls in dbGaP SZ GAIN
1141 cases and 1379 ctls in dbGaP SZ Non-GAIN
748 in NIMH SZ DS 13
848 in exome seq dbGap ARRA
946 in dbGap NIMH-CTL Exome

446 ctls and 352 cases  in dbGap jointGWinMGS

26 in SICCA NIMH CN 3

382 in SZ DS31_1

Released in SZ Dist. 6.0 and Controls Dist
Study 76 Genomic Psychiatry Cohort (GPC) Controls Pato, Pato, Knowles, Marder, Rapaport, Perkins, Buckley, Morley, Bromet, Lehrer, Malaspina, Escamilla, Nicolini 3R01MH085548-03S1 251,262-269, 271, 351-352 19657 Updates received 2016-12-02, in processing; Part 1 Released in SZ Dist. 13.0 and Controls Dist. 8.0
Study 77 International Cohort Collection for Bipolar Disorder Controls Smoller, Sklar, Pato, Knowles, Bromet, Rapaport, Buckley, Escamilla, Morley, Dewan, Lehrer, Marder, Perkins, Malaspina, Nicolini R01MH085542 252, 270, 272-275, 304-312 8947 Updated data received 2016-12-02, in processing; Part 1 released in BP Dist. 10.0 and Controls Dist. 8.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 19 STEP-BD; Treatment of Bipolar Disorder Controls Sachs, Nimgaonkar N01MH080001 14, 78, 86, Site 88-Controls 2365

847 cases and 453 ctls in STEP-BD GWAS; 486 in NIMH Controls DS 1;  105 in dbGap NIMH-CTL Exome;

Released in BP Dist. 6.0 (Site 78)/Controls Dist. 6.0 (Site 88); Sites 14 & 86 not released yet
Study 76 Genomic Psychiatry Cohort (GPC) Controls Pato, Pato, Knowles, Marder, Rapaport, Perkins, Buckley, Morley, Bromet, Lehrer, Malaspina, Escamilla, Nicolini 3R01MH085548-03S1 251,262-269, 271, 351-352 19657 Updates received 2016-12-02, in processing; Part 1 Released in SZ Dist. 13.0 and Controls Dist. 8.0
Study 77 International Cohort Collection for Bipolar Disorder Controls Smoller, Sklar, Pato, Knowles, Bromet, Rapaport, Buckley, Escamilla, Morley, Dewan, Lehrer, Marder, Perkins, Malaspina, Nicolini R01MH085542 252, 270, 272-275, 304-312 8947 Updated data received 2016-12-02, in processing; Part 1 released in BP Dist. 10.0 and Controls Dist. 8.0
Study 137 Genomics of Schizophrenia in the South African Xhosa Controls Stein U01MH096754-01A1 356 2200 Will be released 6 mos. after last subject's sample has been received by repository
Study 140 Genome Sequencing in Extended Bipolar Pedigrees Controls Fremier, Jaramillo, Macaya 3R01MH095454-02S1 435-436 2000 7th RFD email sent 2/8/2017; Using auto-QC email was send 3/9/2016; Will be released 6 mos. after last subject's sample has been received by repository but no later than 11/30/2015
Study 152 Control and Reward Circuits as Targets for Repetitive Thoughts and Behaviors Controls Marsh, Simpson R01MH104648-01 409 80 Will be released 6 mos. after the end of the grant, 2/28/2019
Study 167 Biomarker Assessment of Pomaglumetad on Glutamate Targets: Proof of Clinical Mechanism of Action (POCM) Controls Jeffrey Lieberman, Daniel Javitt, Donald Goff, Stephen Marder, Adrienne Lahti HHSN271201200007I, HHSN27100003, NCT02919774 793-796 81 Will be released to the public no later than 10/28/2017

*Studies in progress includes those available for download for which some future action is required

Depression

Depression Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 7 Genetics of Early-Onset Major Depression Depression Levinson, DePaulo, Sheftner, Crowe, Weissman, Zubenko R01MH060912 80-85 2238 653 in GenRED GWAS Released in DP Dist. 3.0
Study 18 STAR*D; Treatment Resistant Depression Depression Rush N01MH090003 77 1942

962 in NIMH DP DS 2 STAR*D Discovery; 971 in NIMH DP 3 STARD V;

Released in DP Dist. 2.0
Study 20 TADS; Treatment of Adolescents with Depression Depression March 79 Released in DP Dist. 5.0
Study 52 Genetics of Early-Onset Major Depression (GenRED II) Depression DePaulo, Scheftner, Coryell, Weissman, Levinson, Lawson R01MH060912 280-286 1902

450 in GenRED GWAS; 776 in GenRED II GWAS;

Released in DP Dist. 3.0
Study 73 Combining Medications to Enhance Depression Outcomes (CO-MED) Depression Trivedi, Nierenberg, Gaynes, Husain, Preskorn, Kerber, Young, Gilmer, McGrath, Friedman, Zisook, Mitchell, Davis, Lesser, Leuchter, Shelton, Kornstein MH90003 (contract); Combining Medications to Enhance Depression Outcomes 287 650 Released in DP Dist. 5.0
Study 88 Depression Susceptibility Genes and Networks: Expression, eQTL and GWAS Analysis Depression Levinson, Weissman, Potash RC2MH089916 621 1000 937 in GenREDII GWAS,922 in RNAseq Released in DP Dist. 4.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 74 Examination of Genetic and GxE Effects in the Family and Community Health Studies (FACHS) Depression Philibert, Beach R01MH080898 133-134 800 Data received, processing and waiting for PI to clarify questions
Study 83 Incomplete Response in Late Life Depression: Getting to Remission Depression Reynolds, Lenze, Mulsant R01MH083660 277-279 500 Data received; waiting for processing
Study 84 Predictors of Antidepressant Treatment Response: The Emory CIDAR; Predictors of Treatment Response, Relaps, and Recurrence in Major Depression Depression Mayberg, Craighead P50MH077083, R01MH080880 276 500 Data received; waiting for processing
Study 103 Efficacy and Tolerability of Riluzole in Treatment-Resistant Depression Depression Sanacora, Mathew, Fava, Zarate 5R01MH085055, 5R01MH085054, 5R01MH085050 622-625 275 7th RFD email sent 2/8/2017; Due 12/31/2014
Study 105 Establishing Moderators/Biosignatures of Antidepressant Response- Clinical Care (EMBARC) Depression Trivedi, Weissman, McGrath, Parsey, McInnis, Fava U01MH092221, U01MH092250 626-629 400 Will be released 6 mos. after last subject's sample has been received by repository; last sample received 4/7/2016
Study 108 Sustaining Remission of Psychotic Depression Depression Meyers (retired), Rothschild, Whyte, Flint 5U01MH062518, 5U01MH062624, 5U01MH062565, 4U01MH062446 630-633 400 data received, processing not started
Study 113 Identifying Biomarkers for Post-Partum Depression in African-American Women Depression Sullivan, Rubinow R01MH095992 634 2000 2nd RFD email sent 2/8/2017; Will be released 6 mos. after last subject's sample has been received by repository
Study 121 Depression (RAPID LFMS) Depression Fava, Papakostas, Madhukar, Iosifescu, Sanacora, Rapaport, Shelton HHSN271201100006I; Double-Blind, Proof-of-Concept (PIC) Trial of Low Field Magnetic Stimulation (LFMS) Augmentation of Antidepressant Therapy in Treatment-Resistant Depression (TRD) 754-759 90 2nd RFD email sent 2/8/2017; Will be released 6 mos. after last subject's sample has been received by repository
Study 149 Rapidly-Acting Treatments for Treatment-Resistant Depression (RAPID) Depression Fava, Cusin, Iosifescu, Trivedi, Mathew, DeBattista, Sanacora HHSN271201100006I (contract) 760-765 100 Will be released 6 mos. after last subject's sample has been received by repository but no later than 5/15/2016
Study 153 Double-Blind, Placebo-Controlled, Proof-of-Concept (POC) Trial of LY2456302, a Kappa-Selective Opioid Receptor Antagonist, Augmentation of Antidepressant Therapy in Treatment-Resistant Depression (TRD) Depression Fava, Carpenter, Morrison, Zajecka, Macaluso, Shelton HHSN271201100006I 635-639 90 Will be released 6 mos. after last subject’s sample has been received by repository but no later than 2/15/2017
Study 169 Genomics of Postpartum Depression Depression Patrick Sullivan There is no grant number for this study 769 25000 Will be released to the public no later than 6/30/2020

*Studies in progress includes those available for download for which some future action is required

iPSC

iPSC Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 92 Family-Based Genome-Wide Methylation Scan in Neurocognition and Schizophrenia iPSC Gur, Nimgaonkar RC2MH089973, RC2MH089859 320-323 200 Released in iPSC Dist. 6.0
Study 115 Exploring the Neuronal Phenotype of Autism Spectrum Disorders Using Induced Pluri iPSC Hallmayer, Dolmetsch R33MH087898 726 & 734 150 Released in iPSC Dist. 1.0 (2/19/2014) & PMS Dist. 1.0 (4/15/2014)
Study 116 Cellular and genetic correlates of increased head size in autism spectrum disorder iPSC Vaccarino R33MH087879 727 40 Released in iPSC Dist. 2.0
Study 117 Autism iPSCs for Studying Function and Dysfunction in Human Neural Development iPSC Loring R33MH087925 728 8 Released in iPSC Dist. 1.0
Study 125 Analysis of Glutamatergic Neurons Derived from Patient Specific iPS Cells iPSC Lachman, Rapoport R33MH087840 392-393 31 Released in iPSC Dist. 1.0
Study 132 NIMH DIRP Protocol 03-M-0035 Screening, Evaluation, Diagnosis, Treatment Optimization and Follow-Up for Childhood Onset Psychiatric Disorders iPSC Rapoport 1ZIAMH002581 499, 502 270 Released in iPSC Dist. 3.0
Study 143 Modeling Anorexia Nervosa with Human Pluripotent Stem Cells iPSC Muotri R21MH093954-02 408 30 Released in iPSC Dist. 4.0
Study 144 Modeling Autism with Human Pluripotent Cells iPSC Muotri 1DP2OD006495 738 81 Released in iPSC Dist. 4.0
Study 158 Modeling schizophrenia using iPSC neurons iPSC Brennand, Gage Supported by private funds 361 14 Released in iPSC Dist. 5.0
Study 160 Contrasting causal microRNAs in forebrain and midbrain COS hiPSC neural cells iPSC Brennand 5R01MH101454-02 504 50 Released in iPSC Dist. 6.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 127 Target Identification and Validation for Negative Symptoms and Social Cognition in Schizophrenia: A Translational Study iPSC Hahn Target Identification and Validation for Negative Symptoms and Social Cognition in Schizophrenia: A Translational Study 717 50 Send PI subject list 1/9/2017; 6th RFD email sent 2/8/2017; Will be released 6 mos. after last subject's sample has been received by repository
Study 130 Genomics-Guided Characterization of iPS Cells from Common Mental Illnesses iPSC Haggarty, Perlis R21MH093958, R33MH087896 433-434 27 data received Jan 2016, still need more information
Study 131 Chemical genomic approaches to neurobiology of DISC1 iPSC Tsai, Perlis, Cohen R01MH091115 317-318 40 6th RFD email sent 2/8/2017; Using auto-QC email was sent 3/9/2016; Will be released 6 mos. after last subject's sample has been received by repository
Study 136 Integrative Molecular and Phenotype Analysis of 22q11.2 Deletion Syndrome iPSC Hallmayer R01MH100900 355 180 iPSC lines-2 mos. after publication of relevant studies but no later than 2/1/2017; LCLs and fibroblasts (samples submitted by 8/1/2015)-will be released on 10/1/2015; LCLs and fibroblasts (all remaining samples, which should be submitted by 2/1/2017)-will be released on 4/1/2017
Study 145 Genetically Engineered Human Pluripotent Stem Cells as a Platform to Define the B iPSC Jaenisch R01MH104610 737 5 No later than 9/30/2019
Study 146 Induced Neuronal Cells: A Novel Approach to Study Neuropsychiatric Diseases iPSC Wernig/Südhof R01MH092931 741 12 6th RFD email sent 2/8/2017; Released no later than 10/31/2015
Study 159 A chimeric brain model to study human neurological diseases iPSC Muotri 1R21MH107771-01 742 6 Will be released at publication but no later than project end (2015-08-31), whichever comes first
Study 161 iPSC Derived Human Cortical Interneurons as Developmental Model of Schizophrenia iPSC Sangmi Chung 1R01MH107884-01 362-363 7 Will be released 3 mos. after submissions are complete but no later than 8/31/2020
Study 163 Neuropsychiatric Genome-Scale and RDoC Individualized Domains (N-GRID) iPSC Isaac Kohane, Roy Perlis 5P50MH106933 416 400 Will be released 3 mos. after the last sample is received but no later than 10/31/2019
Study 165 Neural development of human induced pluripotent stem cells from schizophrenia patients iPSC Hongjun Song, Russell Margolis R21/R33MH087874 369 13 4th RFD email sent 1/9/2017; Released no later than 4/30/2016
Study 166 Juvenile Onset Schizophrenia iPSCs iPSC Paul Tesar 370 23 Send PI instructions about data submission 1/10/2017, no blood yet; 4th RFD email sent 1/9/2017; Samples and data can be released immediately; 14 skin fibroblasts and 9 iPSCs
Study 173 Collaboration on Preclinical Autism Cellular Assays, Biosignatures, and Network Analyses (COPACABANA) iPSC Eugene W. Yeo/Lawrence Goldstein 1U19MH107367-01 778 19 Will be released to the public no later than 2/26/2020
Study 176 iPSC Phenotype, Mitochondrial Haplotype and Psychosis in 22q11 Deletion Syndrome iPSC Stewart A. Anderson R01MH110185-01 781 9 Will be released to the public no later than 8/31/2019
Study 177 Mitochondrial Dysfunction in Schizophrenia iPSC Marquis Philip Vawter 2R01MH085801-06A1 782 12 Will be released to the public no later than 6/30/2021

*Studies in progress includes those available for download for which some future action is required

Netherlands Twin Register

Netherlands Twin Register Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 78 Netherlands Twin Register Netherlands Twin Register Boomsma, de Geus R01D0042157-01A 169 8540 Released in NTR Dist. 1.0

In Progress*

No studies found.

OCD

OCD Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 16 Collaborative OCD Genetic Study OCD Nestadt, Murphy, Rauch, Greenberg, Fyer/Knowls, McCracken R01MH050214 64-69, 164 1351 Released in OCD Dist. 1.0 (Sites 64-69 and 164); site 164 was under site id 64.
Study 66 OCD Collaborative Genetics Association Study OCD Nestadt, Greenberg, Fyer, Pauls, McCracken R01MH071507 240-244 3395 Released in OCD Dist. 2.0
Study 93 Identifying Intermediate Phenotypes for Compulsive Hoarding OCD Mathews R21MH087748 245 135 Released in Compulsive Hoarding Dist. 1.0 under OCD group
Study 134 Genetic Study of Trichotillomania OCD Scharf, Keuthen Funded by the Trichotillomania Learning Center (TLC). 508, 788, 790 938 Site 508 released in Trichotillomania Distribution 1.0 under OCD group; Sites 788 & 790 will be released no later than 6/16/2020

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 110 D-Cycloserine Augmentation of CBT for Pediatric OCD OCD Geller, Storch R01MH093402, R01MH093381 249-250 150 Data received through QC 8/10/2016, clinical trials data will be from NIMH; qc email 4/26/2016;RFD 6/13/2016;Will be released 6 mos. after last subject's sample has been received by repository
Study 119 Attaining and Maintaining Wellness in OCD OCD Simpson, Foa R01MH045436, R01MH045404 401-402 140 3rd RFD 11/7/2016; qc email 4/26/2016; RFD 6/13/2016 & 9/7/2016; Will be released 6 mos. after last subject's sample has been received by repository
Study 134 Genetic Study of Trichotillomania OCD Scharf, Keuthen Funded by the Trichotillomania Learning Center (TLC). 508, 788, 790 938 Site 508 released in Trichotillomania Distribution 1.0 under OCD group; Sites 788 & 790 will be released no later than 6/16/2020
Study 138 Identification of rare variants of OCD OCD Nedstadt R01MH097993-01A1 406 160 Will be released 6 mos. after last subject's sample has been received by repository but no later than 6/30/2018
Study 139 Addition of OCD to the Genomic Psychiatry Cohort OCD M. Pato, Knowles, Nurmi, Nicolini, Richter R01MH103657 407, 417, 783, 787, 805 5000 Will be released 6 mos. after last subject's sample has been received by repository but no later than 2/1/2020
Study 152 Control and Reward Circuits as Targets for Repetitive Thoughts and Behaviors OCD Marsh, Simpson R01MH104648-01 409 80 Will be released 6 mos. after the end of the grant, 2/28/2019

*Studies in progress includes those available for download for which some future action is required

Phelan-McDermid Syndrome

Phelan-McDermid Syndrome Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 115 Exploring the Neuronal Phenotype of Autism Spectrum Disorders Using Induced Pluri Phelan-McDermid Syndrome Hallmayer, Dolmetsch R33MH087898 726 & 734 150 Released in iPSC Dist. 1.0 (2/19/2014) & PMS Dist. 1.0 (4/15/2014)

In Progress*

No studies found.

RDoC

RDoC Home Page | Top

Available for Download

No studies found.

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 70 Consortium for Neuropsychiatric Phenomics RDoC Bilder 1UL1RR024911 182 2100 RFD sent 9/7/2016
Study 120 RDoC Constructs: Neural Substrates, Heritability, and Relation to Psychopathology RDoC Zald, Lahey R01MH098098 500 400 Will be released 6 mos. after last subject's sample has been received by repository
Study 142 Psychosis and Affective Research Domains and Intermediate Phenotypes (PARDIP) RDoC Tamminga, Keshavan, Pearlson R01MH096913-01A1 496-498 405 Due 12 mos. after last subject's sample has been received by repository but no later than 10/1/2017
Study 147 Longitudinal Family/Molecular Genetic Study to Validate Research Domain Criteria RDoC Glatt/Faraone 1R01MH101519-01A1 501 2800 Will be released 6 mos. after the project end date, 3/31/2019
Study 154 FAST MAS KOR Phase 2a RDoC Krystal, Sanacora, Lisanby, Calabrese, Mathew, Nurnberger, Goodman HHSN271201100006I 410-415 90 2nd RFD 7/25/2016; RFD 6/10/2016; Will be released 6/28/2017
Study 157 Neuroinflammation and Aggression (RDoC) RDoC Coccaro 1R01MH104673-01A1 503 150 Will be released 3 mos. after last subject’s sample has been received by repository but no later than 10/1/2019
Study 171 Genetic Contributions of Negative Valence Systems to Internalizing Pathways RDoC Roxann Roberson-Nay 5R01MH101518 771 800 Will be released to the public no later than 1/31/2018

*Studies in progress includes those available for download for which some future action is required

Schizophrenia

Schizophrenia Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
SZ 0 Linkage Studies of Schizophrenia Schizophrenia Tsuang, Cloninger, Kaufmann 5U01MH046318, 5U01MH046276, 5U01MH046289 30-32 877

35 in dbGaP SZ GAIN;73 in dbGap SZ non-GAIN;

Released in SZ Dist. 1.0
Study 3 Genetic Linkage Study of Schizophrenia Schizophrenia Tsuang M R01MH059624 Site 34-China; Site 35-Taiwan 2328 Site 35 (Taiwan) Released; Site 34 (China) not released yet
Study 6 Molecular Genetics of Schizophrenia Schizophrenia Gejman, Murphy, Mowry, Freedman, Amin, Byerley, Black, Silverman, Levinson, Cloninger R01MH059571 40-49 1383

275 in dbGaP GAIN; 196 in dbGaP Non-GAIN;29 in dbGap jointGWinMGS;

Released
Study 9 A study of Schizophrenia Schizophrenia Weinberger (original PI: Egan) 39 Released in SZ Dist. 12.0
Study 12 Genetic Analysis of Psychosis Schizophrenia Pato R01MH052618 33 233 Released
Study 13 Genetics of Schizophrenia in Latino Populations Schizophrenia Escamilla, Raventos, Munoz, Ontiveros, Nicolini, Mendoza, Jerez, Canive R01MH060881 17, 53-59 1241 Released in SZ Dist. 5.0
Study 15 A Neurobehavioral Family Study of Schizophrenia Schizophrenia Gur, Nimgaonkar R01MH042191 70-71 645 Released in SZ Dist. 5.0; still collecting samples
Study 17 CATIE; Replication of Schizophrenia Associations in CATIE Schizophrenia Lieberman, Sullivan N01MH090001, R01MH074027 Site 75-AD; Site 76-SZ 741

741 in NIMH SZ DS 13 (CATIE);291 in NIMH SZ 27;

Site 76 (SZ) released; Site 75 (AD) released in AD Dist. 3.0
Study 22 PAARTNERS; Schizophrenia Liability Genes Among African Americans Schizophrenia Go, Nimgaonkar, Kwentus, Edwards, McEvoy, Bradford, Santos, Devlin R01MH066181 101-109 1739

12 in dbGap Exome seq in SZ fam;

Released in SZ Dist. 7.0
Study 23 Genetic Susceptibility in Schizophrenia Schizophrenia Nimgaonkar R01MH056242 73 489 Released in SZ Dist. 8.0 and Controls Dist
Study 27 The Genetics of Endophenotypes and Schizophrenia Schizophrenia Braff, Freedman, Tsuang M., Green, Siever, Gur, Tsuang D. R01MH065571 122-128 (COGS 1), 253-257 (COGS 2) 2000

202 in dbGap Exome seq in SZ fam;

COGS1 (sites 122-128) released in SZ Dist. 14.0; COGS2 (sites 253-257) still need data
Study 29 Molecular Genetics of Schizophrenia Schizophrenia Gejman, Levinson, Buccola, Mowry, Freedman, Amin, Byerley, Crowe, Silverman, Cloninger R01MH059571 139-150 8989

 

1212 in NIMH Controls DS 1
463 in NIMH DS 2
1705 in dbGaP BP GAIN
1033 in STEP-BD GWAS
461 in GWAS Pritzker 1
311 in GWAS Pritzker 2
2142 cases and 2332 ctls in dbGaP SZ GAIN
1141 cases and 1379 ctls in dbGaP SZ Non-GAIN
748 in NIMH SZ DS 13
848 in exome seq dbGap ARRA
946 in dbGap NIMH-CTL Exome

446 ctls and 352 cases  in dbGap jointGWinMGS

26 in SICCA NIMH CN 3

382 in SZ DS31_1

Released in SZ Dist. 6.0 and Controls Dist
Study 42 A Genome Wide SNP Association Study: Schizophrenia Schizophrenia Pulver R01MH068406 185 197 Released in SZ Dist. 9.0
Study 59 High-Density Genome-Wide Association Study of Schizophrenia in Large Dutch Sample Schizophrenia Ophoff R01MH078075 100 331 Released in SZ Dist. 10.0
Study 68 Biological Prediction of Psychosis Susceptibility among Adolescent Cannabis Users Schizophrenia DeLisi R01DA021576 18, 131 320 Released in SZ Dist. 14.0
Study 72 Prediction of Relapse in Schizophrenia Schizophrenia Miller, Buckley, Goff, Lauriello, Manschreck, Mendelowitz, Wilson, Kopelowicz 3U01MH070010 261 230 Released in SZ Dist. 16.0
Study 76 Genomic Psychiatry Cohort (GPC) Schizophrenia Pato, Pato, Knowles, Marder, Rapaport, Perkins, Buckley, Morley, Bromet, Lehrer, Malaspina, Escamilla, Nicolini 3R01MH085548-03S1 251,262-269, 271, 351-352 19657 Updates received 2016-12-02, in processing; Part 1 Released in SZ Dist. 13.0 and Controls Dist. 8.0
Study 82 Expanding Rapid Ascertainment Networks of Schizophrenia Families in Taiwan Schizophrenia Tsuang M., Hwu R01MH085560 183 12000 Released in SZ Dist. 15.0
Study 85 Language and Risk in Schizophrenia Schizophrenia DeLisi R21MH083205 260 90 Released in SZ Dist. 14.0
Study 91 Whole-genome sequencing for rare highly penetrant gene variants in schizophrenia Schizophrenia Goldstein RC2MH089915 258-259 110 Released in SZ Dist. 11.0
Study 92 Family-Based Genome-Wide Methylation Scan in Neurocognition and Schizophrenia Schizophrenia Gur, Nimgaonkar RC2MH089973, RC2MH089859 320-323 200 Released in iPSC Dist. 6.0
Study 94 Common and rare variant genetic screens for clozopine-induced agranulocytosis (CIAC) Schizophrenia Sullivan, Lieberman, Malhotra, Kennedy R01MH080403 324-326 1000

22 in SZ DS31_1; 282 in SZ DS31_2;282 in SZ DS31_3;

Released in SZ Dist. 17.0
Study 104 Comparison of Long-Acting Injectable Medications for Schizophrenia (ACLAIMS) Schizophrenia Stroup, Lawrence, Byerly, Caroff, D'Souza, Khan, Lamberti, Lieberman, McEvoy, Miller, Steinbook, Jarskog, Buckley, Desouza, D'Mello, Grabowski, Hicks, Hoblyn, Konicki, Tran, Wilson, Millet R01MH081107 327-347 360 Released in SZ Dist. 16.0
Study 158 Modeling schizophrenia using iPSC neurons Schizophrenia Brennand, Gage Supported by private funds 361 14 Released in iPSC Dist. 5.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 9 A study of Schizophrenia Schizophrenia Weinberger (original PI: Egan) 39 Released in SZ Dist. 12.0
Study 15 A Neurobehavioral Family Study of Schizophrenia Schizophrenia Gur, Nimgaonkar R01MH042191 70-71 645 Released in SZ Dist. 5.0; still collecting samples
Study 27 The Genetics of Endophenotypes and Schizophrenia Schizophrenia Braff, Freedman, Tsuang M., Green, Siever, Gur, Tsuang D. R01MH065571 122-128 (COGS 1), 253-257 (COGS 2) 2000

202 in dbGap Exome seq in SZ fam;

COGS1 (sites 122-128) released in SZ Dist. 14.0; COGS2 (sites 253-257) still need data
Study 67 Population Based Mapping of Schizophrenia Genes Schizophrenia Escamilla, Raventos R01MH061884 129 1500 7th RFD sent 2/8/2017; Due 4/1/2012
Study 76 Genomic Psychiatry Cohort (GPC) Schizophrenia Pato, Pato, Knowles, Marder, Rapaport, Perkins, Buckley, Morley, Bromet, Lehrer, Malaspina, Escamilla, Nicolini 3R01MH085548-03S1 251,262-269, 271, 351-352 19657 Updates received 2016-12-02, in processing; Part 1 Released in SZ Dist. 13.0 and Controls Dist. 8.0
Study 90 A genome-wide association study of Schizophrenia in Ireland Schizophrenia Riley, Corvin, O'Neill R01MH083094 301-302 1500

Received GWAS data on portable hard drive on 7-22-2015

Updated clinical data for both GWAS and NIMH new collected data received 12/18/2015
Study 107 RAISE - Early Treatment Program (ETP) Genetics Schizophrenia Kane, et al. HHSN-271-2009-00019C 350 (all 32 sites using site # 350; have subsite #s) 400 data received, processing not started
Study 122 Characterization of a Mendelian Form of Psychosis in a Population Isolate Schizophrenia Raventos, Glahn, Almasy R56MH097940 319 200 2nd RFD email sent 2/8/2017; Will be released 6 mos. after last subject's sample has been received by repository
Study 124 Multi-pronged genetic studies of schizophrenia in an inbred population Schizophrenia Mansour, Nimgaonkar R01MH093246 349 760 2nd RFD email sent 2/8/2017; Will be released 6 mos. after last subject's sample has been received by repository
Study 137 Genomics of Schizophrenia in the South African Xhosa Schizophrenia Stein U01MH096754-01A1 356 2200 Will be released 6 mos. after last subject's sample has been received by repository
Study 148 Identifying Regulatory Mutations that Influence Neuropsychiatric Disease Schizophrenia Goldstein, Pulver, Levy U01MH105670-01 357-359 340 Due 3 mos. after last subject's sample has been received by repository but no later than 11/30/2018
Study 150 A Study of Schizophrenia Schizophrenia Sullivan, Josiassen There is no grant number associated with this study 354 500 phenotype data received, waiting for related documentations
Study 155 Gene Networks Influencing Psychotic Dysconnectivity in African Americans Schizophrenia Glahn R01MH106324-01 360 750 Will be released 6 mos. after last subject’s sample has been received by repository but no later than 2/28/2020
Study 156 Transferred from Coriell Collection Schizophrenia DeLisi, Gershon Site 735 (BP); Site 736 (SZ) 2500 Data received, waiting on PI resolve issues, 2016-3-2 contacted with excel files, 2016-5-23 send follow-up emails
Study 162 Bipolar-Schizophrenia Network for Intermediate Phenotypes 2 (BSNIP2) Schizophrenia Tamminga, Clementz, Gershon, Keshavan, Pearlson, 364-368 3600 Will be released no later than 12 mos. after the end of the project, 3/31/2015

*Studies in progress includes those available for download for which some future action is required

Fear and Anxiety

Fear and Anxiety Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 61 Molecular Genetic Studies of Human Anxiety Disorder Fear and Anxiety Weissman P01MH60970 137 700 Released in Fear & Anxiety Dist. 1.0
Study 62 Molecular Genetic Studies of Human Anxiety Disorder Fear and Anxiety Fyer P01MH60970 138 470 Released in Fear & Anxiety Dist. 1.0

In Progress*

No studies found.

Suicide

Suicide Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 80 Suicidal Behavior in Mood Disorders: Genes and Intermediate Phenotypes Suicide Mann, Turecki, Rujescu R01MH082041 288-290 1100 Released in Suicide Dist. 1.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 141 Genetic Analysis of High-Risk Utah Suicide Pedigrees Suicide Coon R01MH099134 315 5100 Will be released 6 mos. after last subject's sample has been received by repository but no later than 11/30/2018

*Studies in progress includes those available for download for which some future action is required

Tourette Syndrome

Tourette Syndrome Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 106 Collaborative genomic studies of Tourette Disorder Tourette Syndrome State, Heiman, Brown, Gilbert, Hoskstra, Visser, Mir, Morer, Roessner, Ludolph, Munchau, Heyman, Hedderly, von Plessen, Koh, Kim, Song, Choen, Song, Hong, Kim, Kim, Kuperman, Grice, Zinner, Coffey, Leventhal R01MH092290, R01MH092291, R01MH092292, R01MH092293, R01MH092513, R01MH092516, R01MH092520, R01MH092289, U24MH068457 600-609 (active sites); 610-620 (reserved) 1548 Released in TS Dist. 1.0 (sites 600-609)

In Progress*

No studies found.

22q11.2 Deletion Syndrome

22q11.2 Deletion Syndrome Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 111 Biomarkers for Psychosis in Velo-cardio-facial Syndrome 22q11.2 Deletion Syndrome Kates R01MH064824 394 60 Released in 22q11.2DS Dist. 1.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 99 Brain-Behavior and Genetic Studies of the 22q11DS 22q11.2 Deletion Syndrome Gur, Emanuel U01MH087626 247-248 1000 6th RFD sent 2/8/2017; QC ML sent 2016-04-26; Due 10/1/2016
Study 136 Integrative Molecular and Phenotype Analysis of 22q11.2 Deletion Syndrome 22q11.2 Deletion Syndrome Hallmayer R01MH100900 355 180 iPSC lines-2 mos. after publication of relevant studies but no later than 2/1/2017; LCLs and fibroblasts (samples submitted by 8/1/2015)-will be released on 10/1/2015; LCLs and fibroblasts (all remaining samples, which should be submitted by 2/1/2017)-will be released on 4/1/2017
Study 170 Cognitive-Affective Psychosis Proneness Risk and Protective Factors in 22q11.2DS 22q11.2 Deletion Syndrome Tony J. Simon 1R01MH107108-1 770 150 Will be released to the public no later than 1/31/2021

*Studies in progress includes those available for download for which some future action is required

Psychosis

Psychosis Home Page | Top

Available for Download

No studies found.

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 81 Predictors and Mechanisms of Conversion to Psychosis (NAPLS) Addington, Walker, Seidman, Mathalon, Cannon, Cadenhead, Perkins, Woods, Cornblatt R01MH082004 291-298 960 6th RFD sent 2/8/2017; Samples and data released for sharing 12 mos. after receipt
Study 151 Predictors and Mechanisms of Conversion to Psychosis Cannon, Bearden, Walker, Perkins, Cadenhead, Addington, Cornblatt, Woods, Mathalon, Seidman 2R01MH081902-06A1 486-494 540 Will be released at time of publication or within 3 mos. of the project's end (2/1/2020), whichever comes first
Study 174 The Role of Dysmyelination in Cognitive Impairment of Psychotic Disorders Mariana Lazar 1R01MH108962-01 779 210 Will be released to the public no later than 5/30/2021

*Studies in progress includes those available for download for which some future action is required

PTSD

PTSD Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 87 Emory-MSSM-GSK-NIMH Collaborative Mood and Anxiety Disorders Initiative PTSD Mayberg, Dunlo, Iofescu, Mathew, Neyland U19MH069056 299-300, 313-314 154 Released in PTSD Dist. 1.0 (11/8/2016)

In Progress*

No studies found.

Rutgers University Rutgers University USC Information Sciences Institute Washington University in St.Louis National Institute of Mental Health