NRGR Studies by Distribution

Distribution Studies Total Target Sample Size
ADHD 5 4954
Alzheimer's Disease 2 2152
Anorexia Nervosa 5 4485
Autism 43 23478
Bipolar Disorder 19 31680
Brain Function 8 14600
Controls 9 44808
Depression 17 37887
iPSC 29 2088
Netherlands Twin Register 1 8540
OCD 9 11349
Phelan-McDermid Syndrome 1 150
RDoC 7 6745
Schizophrenia 37 69424
Fear and Anxiety 2 1170
Suicide 2 6200
Tourette Syndrome 1 1548
22q11.2 Deletion Syndrome 4 1390
Psychosis 3 1710
PTSD 1 154

ADHD

ADHD Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 25 International Multi-Center ADHD Genetics Project (IMAGE) ADHD Faraone, Ebstein, Oades, Roeyer, Asherson, Steinhausen, Rothenberger, Gill, Buitelaar, Miranda R01MH062873 19, 90-99 4954

2694 in dbGaP GAIN

Released in ADHD Dist. 1.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 45 Detection of Susceptibility Genes in ADHD ADHD Sandra Loo (new PI) 5R01MH058277-10 135 Data processing - final stages

*Studies in progress includes those available for download for which some future action is required

Alzheimer's Disease

Alzheimer's Disease Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
AD 0 Genetic Studies of Alzheimer's Disease Alzheimer's Disease Albert, Bassett, Go 5U01MH046281, 5U01MH046290, 5U01MH046373 50-52 1411 Released in AD Dist. 1.0
Study 17 CATIE; Replication of Schizophrenia Associations in CATIE Alzheimer's Disease Lieberman, Sullivan N01MH090001, R01MH074027 Site 75-AD; Site 76-SZ 741

741 in NIMH SZ DS 13 (CATIE);291 in NIMH SZ 27;

Site 76 (SZ) released; Site 75 (AD) released in AD Dist. 3.0

In Progress*

No studies found.

Anorexia Nervosa

Anorexia Nervosa Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 24 Genetics of Anorexia Nervosa Anorexia Nervosa Kaye, Fichter, Brandt, Jones, Mitchell, Berrettini, Johnson, Strober, Halmi, Kaplan, Devlin R01MH066122 110-120 1205 Released in ANX Dist. 1.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 96 Olanzapine Versus Placebo in Outpatients with Anorexia Nervosa Anorexia Nervosa Attia, Steinglass, Guarda, Marcus, Kaplan R01MH085921 395-399 160 Data will be deposited within 3 months from end of data preparation
Study 98 The Effects of Estradiol on Genetic Risk for Disordered Eating during Puberty Anorexia Nervosa Klump R01MH092377 246 700 Data received 2014-03-06, updates needed; 6 mos. after last subject's sample has been received by repository

*Studies in progress includes those available for download for which some future action is required

Autism

Autism Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 4 Collaborative Linkage Study of Autism Autism Folstein (retired), Piven, Sutcliffe R01MH055135 60-61, 89 665

26 in exome seq dbGap ARRA; 12 in dbGaP AGP; 515 in NIMH AU DS3; 12 in dbGaP phs000436;

Released
Study 10 Collaborative Linkage Study in Autism Autism Folstein R01MH055135 62 4

4 in NIMH AU DS3;

Released
Study 14 Molecular Genetics of Infantile Autism Autism Myers R01MH052708 63 563

334 in NIMH AU DS3;

49 in dbGaP ARRA;

Released
Study 21 AGRE; A Genomewide Search for Autism Susceptibility Loci Autism Geschwind R01MH064547 72, 74 3908

442 in exome seq dbGap ARRA; 96 in dbGaP AGP; 16 in dbGap phs000639; 362 in NIMH AU DS3;

Released in AU Dist. 7.0
Study 30 A study of Autism Autism Rodier 158 50 Released in AU Dist. 5.0
Study 31 A study of Autism Autism Rodier 151 79 Released in AU Dist. 5.0
Study 32 A study of Autism Autism Szatmari 152 483

31 in exome seq dbGap ARRA;8 in dbGaP AGP;

Released in AU Dist. 5.0
Study 33 Longitudinal Study of Language and Theory of Mind in Autism Autism Tager-Flusberg P01DC003610 153 210

17 in NIMH AU DS3;

Released in AU Dist. 5.0
Study 34 Neurobiology and Genetics of Autism Autism Dawson U19HD035465 154 214

10 in dbGaP ARRA;

Released in AU Dist. 5.0
Study 35 Molecular and Genetic Epidemiology of Autism Autism Pericak-Vance R01MH080647 155 1220 Released in AU Dist. 8.0
Study 36 A study of Autism Autism McInnis 156 310

4 in exome seq dbGap ARRA;

Released in AU Dist. 5.0
Study 37 RUPP-PI Autism McDougle U10MH066766 157 133

27 in exome seq dbGap ARRA;

Released in AU Dist. 5.0
Study 39 A study of Autism Autism Brzustowicz RC1MH088288 161 Released in AU Dist. 13.0
Study 41 The Development of the Siblings of Children with Autism: A Longitudinal Study Autism King, Hollander, Sigman, Piven, Volkmar, Tager-Flusberg, Hollander P50HD055784 700-707 438

7 in exome seq dbGap ARRA;

Site 702 still collecting samples, project end date is 31-MAY-2017; Sites 700-705, 707 were released in AU Dist 6.0
Study 44 Genetic Analysis of 15q11-q13 in Autism Autism Sutcliffe R01MH061009 165

 134 in dbGaP AGP; 71 in dbGaP phs000436;

Released in AU Dist. 12.0
Study 46 DM-STAT (data coordinating site for Studies 30, 31, 33, 34 & 41) Autism Dagher Released in AU Dist. 5.0 and 6.0
Study 50 Genetics of Autism Intermediate Phenotypes Autism Coon, Hepburn R01MH069359 200-201 1711

129 in exome seq dbGap ARRA;

Released in AU Dist. 9.0
Study 56 Clinical and Immunological Investigations of Subtypes of Autism Autism Swedo, Thurm, Amaral Clinical and Immunological Investigations of Subtypes of Autism 163, 208 Released in AU Dist. 14.0
Study 60 A study of Autism Autism Piven 167 275 Released in AU Dist. 14.0
Study 63 Interdisciplinary Studies of Insistence on Sameness in Autism Spectrum Disorders Autism Cook P50HD055751 168 250

438 in exome seq dbGap UIC ACE;

Released in AU Dist. 13.0
Study 64 Center for Genomic and Phenomic Studies in Autism Autism Lajonchere, Amaral, Constantino, Roullet, Malow, Sohl, Manning, Murray 5U24MH081810 202-207, 229 1263

1 in exome seq dbGap ARRA;

Data processing - initial stages; Site 202 Released; Sites 203-207, 229 not released yet
Study 65 Trio Autism Simplex Collection (TASC) Autism Geschwind, Szatmari, Cook, Dawson, Poustka, Gallagher, Cuccaro, Vicente, McMahon, Sutcliffe, Buxbaum, Nurnberger Funded by Autism Speaks 210-221 3374

1012 in exome seq dbGap ARRA; 1815 in dbGaP AGP;

Released in AU Dist. 10.0
Study 69 Biological and Information Processing Mechanisms Underlying Autism Autism Minshew P50HD055748 209 Released in AU Dist. 13.0
Study 79 Genotypic and Phenotypic Factors in Autism Spectrum Disorders Autism Davis, Demmer, Caronna, Kunkel, Walsh, Frazier R01MH085143, R01MH083565 222-227 1048

(lingwei note): 411 in exome seq dbGap ARRA;

29JUL2016(wbh): genomic data at NDAR under collection 2029, not for transfer to NRGR, target sequence data stays at NDAR, exome sequence goes to dbgap, according to David Obenshain of NDAR who cites agreement with Walsh lab; no gwas dataset

https://ndar.nih.gov/edit_collection.html?id=2029

 

NDAR Primary Deposit, study continued; first batch Released in AU Dist. 11.0
Study 86 Autism-Spectrum Disorder Genetics Autism Haines Autism-Spectrum Disorder Genetics 230 1500 Released in AU Dist. 14.0
Study 112 The Genetics of Autism: Epilepsy as a Biomarker Autism Devinsky (724-725), Schultz (740) The Genetics of Autism: Epilepsy as a Biomarker 724-725, 740 1200 Released in AU Dist. 14.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 41 The Development of the Siblings of Children with Autism: A Longitudinal Study Autism King, Hollander, Sigman, Piven, Volkmar, Tager-Flusberg, Hollander P50HD055784 700-707 438

7 in exome seq dbGap ARRA;

Site 702 still collecting samples, project end date is 31-MAY-2017; Sites 700-705, 707 were released in AU Dist 6.0
Study 64 Center for Genomic and Phenomic Studies in Autism Autism Lajonchere, Amaral, Constantino, Roullet, Malow, Sohl, Manning, Murray 5U24MH081810 202-207, 229 1263

1 in exome seq dbGap ARRA;

Data processing - initial stages; Site 202 Released; Sites 203-207, 229 not released yet
Study 65 Trio Autism Simplex Collection (TASC) Autism Geschwind, Szatmari, Cook, Dawson, Poustka, Gallagher, Cuccaro, Vicente, McMahon, Sutcliffe, Buxbaum, Nurnberger Funded by Autism Speaks 210-221 3374

1012 in exome seq dbGap ARRA; 1815 in dbGaP AGP;

Released in AU Dist. 10.0
Study 79 Genotypic and Phenotypic Factors in Autism Spectrum Disorders Autism Davis, Demmer, Caronna, Kunkel, Walsh, Frazier R01MH085143, R01MH083565 222-227 1048

(lingwei note): 411 in exome seq dbGap ARRA;

29JUL2016(wbh): genomic data at NDAR under collection 2029, not for transfer to NRGR, target sequence data stays at NDAR, exome sequence goes to dbgap, according to David Obenshain of NDAR who cites agreement with Walsh lab; no gwas dataset

https://ndar.nih.gov/edit_collection.html?id=2029

 

NDAR Primary Deposit, study continued; first batch Released in AU Dist. 11.0

*Studies in progress includes those available for download for which some future action is required

Bipolar Disorder

Bipolar Disorder Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
BP 0 Linkage Studies of Bipolar Disorder Bipolar Disorder Nurnberger, Reich, DePaulo, Gershon 5U01MH046282, 5U01MH046280, 5U01MH046274 10-13 1353

175 in dbGaP BP GAIN; 112 in NIMH BP-DS11 phase1; 174 in NIMH BP-DS11 phase2;

Released in BP Dist. 1.0
Study 1 A Collaborative Genomic Study of Bipolar Disorder Bipolar Disorder Berrettini, Byerley, Coryell, DePaulo, Gershon, Kelsoe, Nurnberger, Reich, Sheftner, Murphy R01MH059545 20-29 1768

387 in dbGaP BP GAIN;  280 in NIMH BP DS11 phase1; 429 in NIMH BP DS11 phase2;

Released
Study 2 Molecular Genetics of Bipolar Disorder Bipolar Disorder Baron R01MH059602 Site 15-US; Site 16-Israel 843

72 in GWAS Pritzker 1, 94 in GWAS Pritzker 2

Released
Study 8 Genetic Analysis of Bipolar Disorder Bipolar Disorder Pato R01MH058693 38 223 Released
Study 19 STEP-BD; Treatment of Bipolar Disorder Bipolar Disorder Sachs, Nimgaonkar N01MH080001 14, 78, 86, Site 88-Controls 2365

847 cases and 453 ctls in STEP-BD GWAS; 486 in NIMH Controls DS 1;  105 in dbGap NIMH-CTL Exome;

Released in BP Dist. 6.0 (Site 78)/Controls Dist. 6.0 (Site 88); Sites 14 & 86 not released yet
Study 40 Bipolar Genome Study (BiGS) Bipolar Disorder Schetner, Gershon, McMahon, Kelsoe, Nurnberger, McInnis, Berrettini, Byerley, Coryell, Lawson, Rice, Univ. of Michigan P50CA89392 from the National Cancer Institute; K02DA021237 from the National Institute of Drug Abuse 170-181 3934

853 in dbGaP BP GAIN

Released in BP Dist. 5.0
Study 49 Genetics of Bipolar Disorder in Latino Populations Bipolar Disorder Escamilla, Medoza, Paso, Paez, Jerez, Raventos, Nicolini, Ontiveros R01MH069856 190-197 2688 Released in BP Dist. 7.0
Study 55 Adolescents at High Risk for Familial Bipolar Disorder Bipolar Disorder Nurnberger, Kastelli, McInnis, Reich R01MH068009 750-753 374 Released in BP Dist. 8.0
Study 71 Bipolar Endophenotypes in Population Isolates Bipolar Disorder Freimer, Macaya, Ospina-Duque R01MH075007 198-199 560 Released in BP Dist. 9.0
Study 75 Lithium Use for Bipolar Disorder: A Randomized Controlled Effectiveness Trial (LiTMUS) Bipolar Disorder Nierenberg, Ostacher,Iosifescu, Thase, Ketter, Bowden, Calabrese, Friedman Lithium Use for Bipolar Disorder: A Randomized Controlled Effectiveness Trial 189 193 Released in BP Dist. 11.0
Study 77 International Cohort Collection for Bipolar Disorder Bipolar Disorder Smoller, Sklar, Pato, Knowles, Bromet, Rapaport, Buckley, Escamilla, Morley, Dewan, Lehrer, Marder, Perkins, Malaspina, Nicolini R01MH085542 252, 270, 272-275, 304-312 8947 Updated data received 2016-12-02, in processing; Part 1 released in BP Dist. 10.0 and Controls Dist. 8.0
Study 123 Acute Psychotherapy for Bipolar II Depression Bipolar Disorder Swartz R01MH084831 432 38 Released in BP Dist. 10.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 19 STEP-BD; Treatment of Bipolar Disorder Bipolar Disorder Sachs, Nimgaonkar N01MH080001 14, 78, 86, Site 88-Controls 2365

847 cases and 453 ctls in STEP-BD GWAS; 486 in NIMH Controls DS 1;  105 in dbGap NIMH-CTL Exome;

Released in BP Dist. 6.0 (Site 78)/Controls Dist. 6.0 (Site 88); Sites 14 & 86 not released yet
Study 48 A study of Bipolar Disorder Bipolar Disorder McMahon, DePaulo, Gershon 186-188 642 Data received 2012; updated data received Sept 2016; still need fix pedigree
Study 77 International Cohort Collection for Bipolar Disorder Bipolar Disorder Smoller, Sklar, Pato, Knowles, Bromet, Rapaport, Buckley, Escamilla, Morley, Dewan, Lehrer, Marder, Perkins, Malaspina, Nicolini R01MH085542 252, 270, 272-275, 304-312 8947 Updated data received 2016-12-02, in processing; Part 1 released in BP Dist. 10.0 and Controls Dist. 8.0
Study 156 Transferred from Coriell Collection Bipolar Disorder DeLisi, Gershon Site 735 (BP); Site 736 (SZ) 2500 Data received, waiting on PI resolve issues, 2016-3-2 contacted with excel files, 2016-5-23 send follow-up emails

*Studies in progress includes those available for download for which some future action is required

Brain Function

Brain Function Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 109 Discovery Science of Human Brain Function Across the Lifespan Brain Function Milham R01MH094639 303 1000 Released in Brain Function Dist. 1.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 58 Genetics of Brain Structure and Function Brain Function Blangero, Glahn R01MH078111, R01MH078143 136 1300 Received data Aug 7, 2015, updates Aug 19, 2015, still need family id.

*Studies in progress includes those available for download for which some future action is required

Controls

Controls Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 19 STEP-BD; Treatment of Bipolar Disorder Controls Sachs, Nimgaonkar N01MH080001 14, 78, 86, Site 88-Controls 2365

847 cases and 453 ctls in STEP-BD GWAS; 486 in NIMH Controls DS 1;  105 in dbGap NIMH-CTL Exome;

Released in BP Dist. 6.0 (Site 78)/Controls Dist. 6.0 (Site 88); Sites 14 & 86 not released yet
Study 23 Genetic Susceptibility in Schizophrenia Controls Nimgaonkar R01MH056242 73 489 Released in SZ Dist. 8.0 and Controls Dist
Study 29 Molecular Genetics of Schizophrenia Controls Gejman, Levinson, Buccola, Mowry, Freedman, Amin, Byerley, Crowe, Silverman, Cloninger R01MH059571 139-150 8989

 

1212 in NIMH Controls DS 1
463 in NIMH DS 2
1705 in dbGaP BP GAIN
1033 in STEP-BD GWAS
461 in GWAS Pritzker 1
311 in GWAS Pritzker 2
2142 cases and 2332 ctls in dbGaP SZ GAIN
1141 cases and 1379 ctls in dbGaP SZ Non-GAIN
748 in NIMH SZ DS 13
848 in exome seq dbGap ARRA
946 in dbGap NIMH-CTL Exome

446 ctls and 352 cases  in dbGap jointGWinMGS

26 in SICCA NIMH CN 3

382 in SZ DS31_1

Released in SZ Dist. 6.0 and Controls Dist
Study 76 Genomic Psychiatry Cohort (GPC) Controls Pato, Pato, Knowles, Marder, Rapaport, Perkins, Buckley, Morley, Bromet, Lehrer, Malaspina, Escamilla, Nicolini 3R01MH085548-03S1 251,262-269, 271, 351-352 19657 Updates received 2016-12-02, in processing; Part 1 Released in SZ Dist. 13.0 and Controls Dist. 8.0
Study 77 International Cohort Collection for Bipolar Disorder Controls Smoller, Sklar, Pato, Knowles, Bromet, Rapaport, Buckley, Escamilla, Morley, Dewan, Lehrer, Marder, Perkins, Malaspina, Nicolini R01MH085542 252, 270, 272-275, 304-312 8947 Updated data received 2016-12-02, in processing; Part 1 released in BP Dist. 10.0 and Controls Dist. 8.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 19 STEP-BD; Treatment of Bipolar Disorder Controls Sachs, Nimgaonkar N01MH080001 14, 78, 86, Site 88-Controls 2365

847 cases and 453 ctls in STEP-BD GWAS; 486 in NIMH Controls DS 1;  105 in dbGap NIMH-CTL Exome;

Released in BP Dist. 6.0 (Site 78)/Controls Dist. 6.0 (Site 88); Sites 14 & 86 not released yet
Study 76 Genomic Psychiatry Cohort (GPC) Controls Pato, Pato, Knowles, Marder, Rapaport, Perkins, Buckley, Morley, Bromet, Lehrer, Malaspina, Escamilla, Nicolini 3R01MH085548-03S1 251,262-269, 271, 351-352 19657 Updates received 2016-12-02, in processing; Part 1 Released in SZ Dist. 13.0 and Controls Dist. 8.0
Study 77 International Cohort Collection for Bipolar Disorder Controls Smoller, Sklar, Pato, Knowles, Bromet, Rapaport, Buckley, Escamilla, Morley, Dewan, Lehrer, Marder, Perkins, Malaspina, Nicolini R01MH085542 252, 270, 272-275, 304-312 8947 Updated data received 2016-12-02, in processing; Part 1 released in BP Dist. 10.0 and Controls Dist. 8.0

*Studies in progress includes those available for download for which some future action is required

Depression

Depression Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 7 Genetics of Early-Onset Major Depression Depression Levinson, DePaulo, Sheftner, Crowe, Weissman, Zubenko R01MH060912 80-85 2238 653 in GenRED GWAS Released in DP Dist. 3.0
Study 18 STAR*D; Treatment Resistant Depression Depression Rush N01MH090003 77 1942

962 in NIMH DP DS 2 STAR*D Discovery; 971 in NIMH DP 3 STARD V;

Released in DP Dist. 2.0
Study 20 TADS; Treatment of Adolescents with Depression Depression March 79 Released in DP Dist. 5.0
Study 52 Genetics of Early-Onset Major Depression (GenRED II) Depression DePaulo, Scheftner, Coryell, Weissman, Levinson, Lawson R01MH060912 280-286 1902

450 in GenRED GWAS; 776 in GenRED II GWAS;

Released in DP Dist. 3.0
Study 73 Combining Medications to Enhance Depression Outcomes (CO-MED) Depression Trivedi, Nierenberg, Gaynes, Husain, Preskorn, Kerber, Young, Gilmer, McGrath, Friedman, Zisook, Mitchell, Davis, Lesser, Leuchter, Shelton, Kornstein MH90003 (contract); Combining Medications to Enhance Depression Outcomes 287 650 Released in DP Dist. 5.0
Study 83 Incomplete Response in Late Life Depression: Getting to Remission Depression Reynolds, Lenze, Mulsant R01MH083660 277-279 500 Released in DP Dist. 6.0
Study 88 Depression Susceptibility Genes and Networks: Expression, eQTL and GWAS Analysis Depression Levinson, Weissman, Potash RC2MH089916 621 1000 937 in GenREDII GWAS,922 in RNAseq Released in DP Dist. 4.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 74 Examination of Genetic and GxE Effects in the Family and Community Health Studies (FACHS) Depression Philibert, Beach R01MH080898 133-134 800 Data received, processing and waiting for PI to clarify questions
Study 84 Predictors of Antidepressant Treatment Response: The Emory CIDAR; Predictors of Treatment Response, Relaps, and Recurrence in Major Depression Depression Mayberg, Craighead P50MH077083, R01MH080880 276 500 Data received; In processing
Study 108 Sustaining Remission of Psychotic Depression Depression Meyers (retired), Rothschild, Whyte, Flint 5U01MH062518, 5U01MH062624, 5U01MH062565, 4U01MH062446 630-633 400 data received, processing not started

*Studies in progress includes those available for download for which some future action is required

iPSC

iPSC Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 92 Family-Based Genome-Wide Methylation Scan in Neurocognition and Schizophrenia iPSC Gur, Nimgaonkar RC2MH089973, RC2MH089859 320-323 200 Released in iPSC Dist. 6.0
Study 115 Exploring the Neuronal Phenotype of Autism Spectrum Disorders Using Induced Pluri iPSC Hallmayer, Dolmetsch R33MH087898 726 & 734 150 Released in iPSC Dist. 1.0 (2/19/2014) & PMS Dist. 1.0 (4/15/2014)
Study 116 Cellular and genetic correlates of increased head size in autism spectrum disorder iPSC Vaccarino R33MH087879 727 40 Released in iPSC Dist. 2.0
Study 117 Autism iPSCs for Studying Function and Dysfunction in Human Neural Development iPSC Loring R33MH087925 728 8 Released in iPSC Dist. 1.0
Study 125 Analysis of Glutamatergic Neurons Derived from Patient Specific iPS Cells iPSC Lachman, Rapoport R33MH087840 392-393 31 Released in iPSC Dist. 1.0
Study 130 Genomics-Guided Characterization of iPS Cells from Common Mental Illnesses iPSC Haggarty, Perlis R21MH093958, R33MH087896 433-434 27 Released in iPSC Dist. 7.0
Study 132 NIMH DIRP Protocol 03-M-0035 Screening, Evaluation, Diagnosis, Treatment Optimization and Follow-Up for Childhood Onset Psychiatric Disorders iPSC Rapoport 1ZIAMH002581 499, 502 270 site 499 Released in iPSC Dist. 3.0; still need site 502.
Study 143 Modeling Anorexia Nervosa with Human Pluripotent Stem Cells iPSC Muotri R21MH093954-02 408 30 Released in iPSC Dist. 4.0
Study 144 Modeling Autism with Human Pluripotent Cells iPSC Muotri 1DP2OD006495 738 81 Released in iPSC Dist. 4.0
Study 158 Modeling schizophrenia using iPSC neurons iPSC Brennand, Gage Supported by private funds 361 14 Released in iPSC Dist. 5.0
Study 160 Contrasting causal microRNAs in forebrain and midbrain COS hiPSC neural cells iPSC Brennand 5R01MH101454-02 504 50 Released in iPSC Dist. 6.0
Study 163 Neuropsychiatric Genome-Scale and RDoC Individualized Domains (N-GRID) iPSC Isaac Kohane, Roy Perlis 5P50MH106933 416 400 Released in iPSC Dist. 7.0

In Progress*

No studies found.

Netherlands Twin Register

Netherlands Twin Register Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 78 Netherlands Twin Register Netherlands Twin Register Boomsma, de Geus R01D0042157-01A 169 8540 Released in NTR Dist. 1.0

In Progress*

No studies found.

OCD

OCD Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 16 Collaborative OCD Genetic Study OCD Nestadt, Murphy, Rauch, Greenberg, Fyer/Knowls, McCracken R01MH050214 64-69, 164 1351

911 in dbGaP OCGAS

Released in OCD Dist. 1.0 (Sites 64-69 and 164); site 164 was under site id 64.
Study 66 OCD Collaborative Genetics Association Study OCD Nestadt, Greenberg, Fyer, Pauls, McCracken R01MH071507 240-244 3395

1539 in dbGap OCGAS;

Released in OCD Dist. 2.0
Study 93 Identifying Intermediate Phenotypes for Compulsive Hoarding OCD Mathews R21MH087748 245 135 Released in Compulsive Hoarding Dist. 1.0 under OCD group
Study 134 Genetic Study of Trichotillomania OCD Scharf, Keuthen Funded by the Trichotillomania Learning Center (TLC). 508, 788, 790 938 Site 508 released in Trichotillomania Distribution 1.0 under OCD group; Sites 788 & 790 will be released no later than 6/16/2020

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 110 D-Cycloserine Augmentation of CBT for Pediatric OCD OCD Geller, Storch R01MH093402, R01MH093381 249-250 150 Data received through QC 8/10/2016, clinical trials data will be from NIMH; Will be released 6 mos. after last subject's sample has been received by repository
Study 134 Genetic Study of Trichotillomania OCD Scharf, Keuthen Funded by the Trichotillomania Learning Center (TLC). 508, 788, 790 938 Site 508 released in Trichotillomania Distribution 1.0 under OCD group; Sites 788 & 790 will be released no later than 6/16/2020

*Studies in progress includes those available for download for which some future action is required

Phelan-McDermid Syndrome

Phelan-McDermid Syndrome Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 115 Exploring the Neuronal Phenotype of Autism Spectrum Disorders Using Induced Pluri Phelan-McDermid Syndrome Hallmayer, Dolmetsch R33MH087898 726 & 734 150 Released in iPSC Dist. 1.0 (2/19/2014) & PMS Dist. 1.0 (4/15/2014)

In Progress*

No studies found.

RDoC

RDoC Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 120 RDoC Constructs: Neural Substrates, Heritability, and Relation to Psychopathology RDoC Zald, Lahey R01MH098098 500 400 Released in RDoC Dist. 1.0

In Progress*

No studies found.

Schizophrenia

Schizophrenia Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
SZ 0 Linkage Studies of Schizophrenia Schizophrenia Tsuang, Cloninger, Kaufmann 5U01MH046318, 5U01MH046276, 5U01MH046289 30-32 877

35 in dbGaP SZ GAIN;73 in dbGap SZ non-GAIN;

Released in SZ Dist. 1.0
Study 3 Genetic Linkage Study of Schizophrenia Schizophrenia Tsuang M R01MH059624 Site 34-China; Site 35-Taiwan 2328 Site 35 (Taiwan) Released; Site 34 (China) not released yet
Study 6 Molecular Genetics of Schizophrenia Schizophrenia Gejman, Murphy, Mowry, Freedman, Amin, Byerley, Black, Silverman, Levinson, Cloninger R01MH059571 40-49 1383

275 in dbGaP GAIN; 196 in dbGaP Non-GAIN;29 in dbGap jointGWinMGS;

Released
Study 9 A study of Schizophrenia Schizophrenia Weinberger (original PI: Egan) 39 Released in SZ Dist. 12.0
Study 12 Genetic Analysis of Psychosis Schizophrenia Pato R01MH052618 33 233 Released
Study 13 Genetics of Schizophrenia in Latino Populations Schizophrenia Escamilla, Raventos, Munoz, Ontiveros, Nicolini, Mendoza, Jerez, Canive R01MH060881 17, 53-59 1241 Released in SZ Dist. 5.0
Study 15 A Neurobehavioral Family Study of Schizophrenia Schizophrenia Gur, Nimgaonkar R01MH042191 70-71 645 Released in SZ Dist. 5.0; still collecting samples
Study 17 CATIE; Replication of Schizophrenia Associations in CATIE Schizophrenia Lieberman, Sullivan N01MH090001, R01MH074027 Site 75-AD; Site 76-SZ 741

741 in NIMH SZ DS 13 (CATIE);291 in NIMH SZ 27;

Site 76 (SZ) released; Site 75 (AD) released in AD Dist. 3.0
Study 22 PAARTNERS; Schizophrenia Liability Genes Among African Americans Schizophrenia Go, Nimgaonkar, Kwentus, Edwards, McEvoy, Bradford, Santos, Devlin R01MH066181 101-109 1739

12 in dbGap Exome seq in SZ fam;

Released in SZ Dist. 7.0
Study 23 Genetic Susceptibility in Schizophrenia Schizophrenia Nimgaonkar R01MH056242 73 489 Released in SZ Dist. 8.0 and Controls Dist
Study 27 The Genetics of Endophenotypes and Schizophrenia Schizophrenia Braff, Freedman, Tsuang M., Green, Siever, Gur, Tsuang D. R01MH065571 122-128 (COGS 1), 253-257 (COGS 2) 2000

202 in dbGap Exome seq in SZ fam;

1 in dbGaP SZ-Gain; 1 in dbGaP SZ-non-Gain;

COGS1 (sites 122-128) released in SZ Dist. 14.0; COGS2 (sites 253-257) still need data
Study 29 Molecular Genetics of Schizophrenia Schizophrenia Gejman, Levinson, Buccola, Mowry, Freedman, Amin, Byerley, Crowe, Silverman, Cloninger R01MH059571 139-150 8989

 

1212 in NIMH Controls DS 1
463 in NIMH DS 2
1705 in dbGaP BP GAIN
1033 in STEP-BD GWAS
461 in GWAS Pritzker 1
311 in GWAS Pritzker 2
2142 cases and 2332 ctls in dbGaP SZ GAIN
1141 cases and 1379 ctls in dbGaP SZ Non-GAIN
748 in NIMH SZ DS 13
848 in exome seq dbGap ARRA
946 in dbGap NIMH-CTL Exome

446 ctls and 352 cases  in dbGap jointGWinMGS

26 in SICCA NIMH CN 3

382 in SZ DS31_1

Released in SZ Dist. 6.0 and Controls Dist
Study 42 A Genome Wide SNP Association Study: Schizophrenia Schizophrenia Pulver R01MH068406 185 197 Released in SZ Dist. 9.0
Study 59 High-Density Genome-Wide Association Study of Schizophrenia in Large Dutch Sample Schizophrenia Ophoff R01MH078075 100 331 Released in SZ Dist. 10.0
Study 68 Biological Prediction of Psychosis Susceptibility among Adolescent Cannabis Users Schizophrenia DeLisi R01DA021576 18, 131 320 Released in SZ Dist. 14.0
Study 72 Prediction of Relapse in Schizophrenia Schizophrenia Miller, Buckley, Goff, Lauriello, Manschreck, Mendelowitz, Wilson, Kopelowicz 3U01MH070010 261 230 Released in SZ Dist. 16.0
Study 76 Genomic Psychiatry Cohort (GPC) Schizophrenia Pato, Pato, Knowles, Marder, Rapaport, Perkins, Buckley, Morley, Bromet, Lehrer, Malaspina, Escamilla, Nicolini 3R01MH085548-03S1 251,262-269, 271, 351-352 19657 Updates received 2016-12-02, in processing; Part 1 Released in SZ Dist. 13.0 and Controls Dist. 8.0
Study 82 Expanding Rapid Ascertainment Networks of Schizophrenia Families in Taiwan Schizophrenia Tsuang M., Hwu R01MH085560 183 12000 Released in SZ Dist. 15.0
Study 85 Language and Risk in Schizophrenia Schizophrenia DeLisi R21MH083205 260 90 Released in SZ Dist. 14.0
Study 91 Whole-genome sequencing for rare highly penetrant gene variants in schizophrenia Schizophrenia Goldstein RC2MH089915 258-259 110

162 in dbGaP phs000682

 

Released in SZ Dist. 11.0
Study 92 Family-Based Genome-Wide Methylation Scan in Neurocognition and Schizophrenia Schizophrenia Gur, Nimgaonkar RC2MH089973, RC2MH089859 320-323 200 Released in iPSC Dist. 6.0
Study 94 Common and rare variant genetic screens for clozopine-induced agranulocytosis (CIAC) Schizophrenia Sullivan, Lieberman, Malhotra, Kennedy R01MH080403 324-326 1000

22 in SZ DS31_1; 282 in SZ DS31_2;282 in SZ DS31_3;

Released in SZ Dist. 17.0
Study 104 Comparison of Long-Acting Injectable Medications for Schizophrenia (ACLAIMS) Schizophrenia Stroup, Lawrence, Byerly, Caroff, D'Souza, Khan, Lamberti, Lieberman, McEvoy, Miller, Steinbook, Jarskog, Buckley, Desouza, D'Mello, Grabowski, Hicks, Hoblyn, Konicki, Tran, Wilson, Millet R01MH081107 327-347 360 Released in SZ Dist. 16.0
Study 158 Modeling schizophrenia using iPSC neurons Schizophrenia Brennand, Gage Supported by private funds 361 14 Released in iPSC Dist. 5.0

In Progress*

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 9 A study of Schizophrenia Schizophrenia Weinberger (original PI: Egan) 39 Released in SZ Dist. 12.0
Study 15 A Neurobehavioral Family Study of Schizophrenia Schizophrenia Gur, Nimgaonkar R01MH042191 70-71 645 Released in SZ Dist. 5.0; still collecting samples
Study 27 The Genetics of Endophenotypes and Schizophrenia Schizophrenia Braff, Freedman, Tsuang M., Green, Siever, Gur, Tsuang D. R01MH065571 122-128 (COGS 1), 253-257 (COGS 2) 2000

202 in dbGap Exome seq in SZ fam;

1 in dbGaP SZ-Gain; 1 in dbGaP SZ-non-Gain;

COGS1 (sites 122-128) released in SZ Dist. 14.0; COGS2 (sites 253-257) still need data
Study 76 Genomic Psychiatry Cohort (GPC) Schizophrenia Pato, Pato, Knowles, Marder, Rapaport, Perkins, Buckley, Morley, Bromet, Lehrer, Malaspina, Escamilla, Nicolini 3R01MH085548-03S1 251,262-269, 271, 351-352 19657 Updates received 2016-12-02, in processing; Part 1 Released in SZ Dist. 13.0 and Controls Dist. 8.0
Study 90 A genome-wide association study of Schizophrenia in Ireland Schizophrenia Riley, Corvin, O'Neill R01MH083094 301-302 1500

Received GWAS data on portable hard drive on 7-22-2015

Updated clinical data for both GWAS and NIMH new collected data received 12/18/2015
Study 107 RAISE - Early Treatment Program (ETP) Genetics Schizophrenia Kane, et al. HHSN-271-2009-00019C 350 (all 32 sites using site # 350; have subsite #s) 400 data received, processing not started
Study 122 Characterization of a Mendelian Form of Psychosis in a Population Isolate Schizophrenia Raventos, Glahn, Almasy R56MH097940 319 200 Phenotypic data received through QC. Watiting for documentations and clarifications from PI
Study 150 A Study of Schizophrenia Schizophrenia Sullivan, Josiassen There is no grant number associated with this study 354 500 phenotype data received, in processing
Study 156 Transferred from Coriell Collection Schizophrenia DeLisi, Gershon Site 735 (BP); Site 736 (SZ) 2500 Data received, waiting on PI resolve issues, 2016-3-2 contacted with excel files, 2016-5-23 send follow-up emails

*Studies in progress includes those available for download for which some future action is required

Fear and Anxiety

Fear and Anxiety Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 61 Molecular Genetic Studies of Human Anxiety Disorder Fear and Anxiety Weissman P01MH60970 137 700 Released in Fear & Anxiety Dist. 1.0
Study 62 Molecular Genetic Studies of Human Anxiety Disorder Fear and Anxiety Fyer P01MH60970 138 470 Released in Fear & Anxiety Dist. 1.0

In Progress*

No studies found.

Suicide

Suicide Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 80 Suicidal Behavior in Mood Disorders: Genes and Intermediate Phenotypes Suicide Mann, Turecki, Rujescu R01MH082041 288-290 1100 Released in Suicide Dist. 1.0

In Progress*

No studies found.

Tourette Syndrome

Tourette Syndrome Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 106 Collaborative genomic studies of Tourette Disorder Tourette Syndrome State, Heiman, Brown, Gilbert, Hoskstra, Visser, Mir, Morer, Roessner, Ludolph, Munchau, Heyman, Hedderly, von Plessen, Koh, Kim, Song, Choen, Song, Hong, Kim, Kim, Kuperman, Grice, Zinner, Coffey, Leventhal R01MH092290, R01MH092291, R01MH092292, R01MH092293, R01MH092513, R01MH092516, R01MH092520, R01MH092289, U24MH068457 600-609 (active sites); 610-620 (reserved) 1548 Released in TS Dist. 1.0 (sites 600-609)

In Progress*

No studies found.

22q11.2 Deletion Syndrome

22q11.2 Deletion Syndrome Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 111 Biomarkers for Psychosis in Velo-cardio-facial Syndrome 22q11.2 Deletion Syndrome Kates R01MH064824 394 60 Released in 22q11.2DS Dist. 1.0

In Progress*

No studies found.

Psychosis

Psychosis Home Page | Top

Available for Download

No studies found.

In Progress*

No studies found.

PTSD

PTSD Home Page | Top

Available for Download

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
Study 87 Emory-MSSM-GSK-NIMH Collaborative Mood and Anxiety Disorders Initiative PTSD Mayberg, Dunlo, Iofescu, Mathew, Neyland U19MH069056 299-300, 313-314 154 Released in PTSD Dist. 1.0 (11/8/2016)

In Progress*

No studies found.

Rutgers University Rutgers University USC Information Sciences Institute Washington University in St.Louis National Institute of Mental Health