List of NIMH Genetic Studies

Study Title Distributions PIs Grants Sites Target Sample Size GWAS Notes Status
BP 0 Linkage Studies of Bipolar Disorder Bipolar Disorder Nurnberger, Reich, DePaulo, Gershon

5U01MH046282, 5U01MH046280, 5U01MH046274

10-13 1353

175 in dbGaP BP GAIN; 112 in NIMH BP-DS11 phase1; 174 in NIMH BP-DS11 phase2;

Released in BP Dist. 1.0
SZ 0 Linkage Studies of Schizophrenia Schizophrenia Tsuang, Cloninger, Kaufmann

5U01MH046318, 5U01MH046276, 5U01MH046289

30-32 877

35 in dbGaP SZ GAIN;73 in dbGap SZ non-GAIN;

Released in SZ Dist. 1.0
AD 0 Genetic Studies of Alzheimer's Disease Alzheimer's Disease Albert, Bassett, Go

5U01MH046281, 5U01MH046290, 5U01MH046373

50-52 1411 Released in AD Dist. 1.0
Study 1 A Collaborative Genomic Study of Bipolar Disorder Bipolar Disorder Berrettini, Byerley, Coryell, DePaulo, Gershon, Kelsoe, Nurnberger, Reich, Sheftner, Murphy

R01MH059545

20-29 1768

387 in dbGaP BP GAIN;  280 in NIMH BP DS11 phase1; 429 in NIMH BP DS11 phase2;

Released
Study 2 Molecular Genetics of Bipolar Disorder Bipolar Disorder Baron

R01MH059602

Site 15-US; Site 16-Israel 843

72 in GWAS Pritzker 1, 94 in GWAS Pritzker 2

Released
Study 3 Genetic Linkage Study of Schizophrenia Schizophrenia Tsuang M

R01MH059624

Site 34-China; Site 35-Taiwan 2328 Site 35 (Taiwan) Released; Site 34 (China) not released yet
Study 4 Collaborative Linkage Study of Autism Autism Folstein (retired), Piven, Sutcliffe

R01MH055135

60-61, 89 665

26 in exome seq dbGap ARRA; 12 in dbGaP AGP; 515 in NIMH AU DS3; 12 in dbGaP phs000436;

Released
Study 5 A study of Schizophrenia (Withdrawn) Schizophrenia Withdrawn 37 Withdrawn
Study 6 Molecular Genetics of Schizophrenia Schizophrenia Gejman, Murphy, Mowry, Freedman, Amin, Byerley, Black, Silverman, Levinson, Cloninger

R01MH059571

40-49 1383

275 in dbGaP GAIN; 196 in dbGaP Non-GAIN;29 in dbGap jointGWinMGS;

Released
Study 7 Genetics of Early-Onset Major Depression Depression Levinson, DePaulo, Sheftner, Crowe, Weissman, Zubenko R01MH060912 80-85 2238 653 in GenRED GWAS Released in DP Dist. 3.0
Study 8 Genetic Analysis of Bipolar Disorder Bipolar Disorder Pato R01MH058693 38 223 Released
Study 9 A study of Schizophrenia Schizophrenia Weinberger (original PI: Egan) 39 Released in SZ Dist. 12.0
Study 10 Collaborative Linkage Study in Autism Autism Folstein

R01MH055135

62 4

4 in NIMH AU DS3;

Released
Study 11 A study of Schizophrenia (Withdrawn) Schizophrenia 36 Withdrawn
Study 12 Genetic Analysis of Psychosis Schizophrenia Pato R01MH052618 33 233 Released
Study 13 Genetics of Schizophrenia in Latino Populations Schizophrenia Escamilla, Raventos, Munoz, Ontiveros, Nicolini, Mendoza, Jerez, Canive R01MH060881 17, 53-59 1241 Released in SZ Dist. 5.0
Study 14 Molecular Genetics of Infantile Autism Autism Myers

R01MH052708

63 563

334 in NIMH AU DS3;

49 in dbGaP ARRA;

Released
Study 15 A Neurobehavioral Family Study of Schizophrenia Schizophrenia Gur, Nimgaonkar

R01MH042191

70-71 645 Released in SZ Dist. 5.0; still collecting samples
Study 16 Collaborative OCD Genetic Study OCD Nestadt, Murphy, Rauch, Greenberg, Fyer/Knowls, McCracken

R01MH050214

64-69, 164 1351

911 in dbGaP OCGAS

Released in OCD Dist. 1.0 (Sites 64-69 and 164); site 164 was under site id 64.
Study 17 CATIE; Replication of Schizophrenia Associations in CATIE Alzheimer's Disease, Schizophrenia Lieberman, Sullivan

N01MH090001, R01MH074027

Site 75-AD; Site 76-SZ 741

741 in NIMH SZ DS 13 (CATIE);291 in NIMH SZ 27;

Site 76 (SZ) released; Site 75 (AD) released in AD Dist. 3.0
Study 18 STAR*D; Treatment Resistant Depression Depression Rush

N01MH090003

77 1942

962 in NIMH DP DS 2 STAR*D Discovery; 971 in NIMH DP 3 STARD V;

Released in DP Dist. 2.0
Study 19 STEP-BD; Treatment of Bipolar Disorder Bipolar Disorder, Controls Sachs, Nimgaonkar

N01MH080001

14, 78, 86, Site 88-Controls 2365

847 cases and 453 ctls in STEP-BD GWAS; 486 in NIMH Controls DS 1;  105 in dbGap NIMH-CTL Exome;

Released in BP Dist. 6.0 (Site 78)/Controls Dist. 6.0 (Site 88); Sites 14 & 86 not released yet
Study 20 TADS; Treatment of Adolescents with Depression Depression March 79 Released in DP Dist. 5.0
Study 21 AGRE; A Genomewide Search for Autism Susceptibility Loci Autism Geschwind

R01MH064547

72, 74 3908

442 in exome seq dbGap ARRA; 96 in dbGaP AGP; 16 in dbGap phs000639; 362 in NIMH AU DS3;

Released in AU Dist. 7.0
Study 22 PAARTNERS; Schizophrenia Liability Genes Among African Americans Schizophrenia Go, Nimgaonkar, Kwentus, Edwards, McEvoy, Bradford, Santos, Devlin

R01MH066181

101-109 1739

12 in dbGap Exome seq in SZ fam;

Released in SZ Dist. 7.0
Study 23 Genetic Susceptibility in Schizophrenia Controls, Schizophrenia Nimgaonkar

R01MH056242

73 489 Released in SZ Dist. 8.0 and Controls Dist
Study 24 Genetics of Anorexia Nervosa Anorexia Nervosa Kaye, Fichter, Brandt, Jones, Mitchell, Berrettini, Johnson, Strober, Halmi, Kaplan, Devlin R01MH066122 110-120 1205 Released in ANX Dist. 1.0
Study 25 International Multi-Center ADHD Genetics Project (IMAGE) ADHD Faraone, Ebstein, Oades, Roeyer, Asherson, Steinhausen, Rothenberger, Gill, Buitelaar, Miranda

R01MH062873

19, 90-99 4954

2694 in dbGaP GAIN

Released in ADHD Dist. 1.0
Study 26 A study of Bipolar Disorder (Withdrawn) Bipolar Disorder Withdrawn 87 Withdrawn
Study 27 The Genetics of Endophenotypes and Schizophrenia Schizophrenia Braff, Freedman, Tsuang M., Green, Siever, Gur, Tsuang D.

R01MH065571

122-128 (COGS 1), 253-257 (COGS 2) 2000

202 in dbGap Exome seq in SZ fam;

1 in dbGaP SZ-Gain; 1 in dbGaP SZ-non-Gain;

COGS1 (sites 122-128) released in SZ Dist. 14.0; COGS2 (sites 253-257) still need data
Study 28 A study of ADHD (CHOP) ADHD Elia

5K23MH066275-05

130

08feb2017: Study 28 (Elias: CHOP) GWAS was one of four sites analyzed by PGC in their 2010 metaanalysis of ADHD, see publication below.  Data will also be available on the NRGR website with ids linked to NRGR cell lines; ids in the current PGC download are not directly linked to NRGR ids.  

pubmed link to PGC ADHD meta-analysis: 

https://www.ncbi.nlm.nih.gov/pubmed/20732625

Data processing - final stages
Study 29 Molecular Genetics of Schizophrenia Controls, Schizophrenia Gejman, Levinson, Buccola, Mowry, Freedman, Amin, Byerley, Crowe, Silverman, Cloninger

R01MH059571

139-150 8989

 

1212 in NIMH Controls DS 1
463 in NIMH DS 2
1705 in dbGaP BP GAIN
1033 in STEP-BD GWAS
461 in GWAS Pritzker 1
311 in GWAS Pritzker 2
2142 cases and 2332 ctls in dbGaP SZ GAIN
1141 cases and 1379 ctls in dbGaP SZ Non-GAIN
748 in NIMH SZ DS 13
848 in exome seq dbGap ARRA
946 in dbGap NIMH-CTL Exome

446 ctls and 352 cases  in dbGap jointGWinMGS

26 in SICCA NIMH CN 3

382 in SZ DS31_1

Released in SZ Dist. 6.0 and Controls Dist
Study 30 A study of Autism Autism Rodier 158 50 Released in AU Dist. 5.0
Study 31 A study of Autism Autism Rodier 151 79 Released in AU Dist. 5.0
Study 32 A study of Autism Autism Szatmari 152 483

31 in exome seq dbGap ARRA;8 in dbGaP AGP;

Released in AU Dist. 5.0
Study 33 Longitudinal Study of Language and Theory of Mind in Autism Autism Tager-Flusberg

P01DC003610

153 210

17 in NIMH AU DS3;

Released in AU Dist. 5.0
Study 34 Neurobiology and Genetics of Autism Autism Dawson

U19HD035465

154 214

10 in dbGaP ARRA;

Released in AU Dist. 5.0
Study 35 Molecular and Genetic Epidemiology of Autism Autism Pericak-Vance

R01MH080647

155 1220 Released in AU Dist. 8.0
Study 36 A study of Autism Autism McInnis 156 310

4 in exome seq dbGap ARRA;

Released in AU Dist. 5.0
Study 37 RUPP-PI Autism McDougle

U10MH066766

157 133

27 in exome seq dbGap ARRA;

Released in AU Dist. 5.0
Study 38 A study of Autism (Withdrawn) Autism Withdrawn 159 Withdrawn
Study 39 A study of Autism Autism Brzustowicz

RC1MH088288

161 Released in AU Dist. 13.0
Study 40 Bipolar Genome Study (BiGS) Bipolar Disorder Schetner, Gershon, McMahon, Kelsoe, Nurnberger, McInnis, Berrettini, Byerley, Coryell, Lawson, Rice, Univ. of Michigan 170-181 3934

853 in dbGaP BP GAIN

Released in BP Dist. 5.0
Study 41 The Development of the Siblings of Children with Autism: A Longitudinal Study Autism King, Hollander, Sigman, Piven, Volkmar, Tager-Flusberg, Hollander

P50HD055784

700-707 438

7 in exome seq dbGap ARRA;

Site 702 still collecting samples, project end date is 31-MAY-2017; Sites 700-705, 707 were released in AU Dist 6.0
Study 42 A Genome Wide SNP Association Study: Schizophrenia Schizophrenia Pulver R01MH068406 185 197 Released in SZ Dist. 9.0
Study 43 A study of ADHD ADHD Todorov, Todd (deceased) 132 Due, in process, send id list to PI
Study 44 Genetic Analysis of 15q11-q13 in Autism Autism Sutcliffe

R01MH061009

165

 134 in dbGaP AGP; 71 in dbGaP phs000436;

Released in AU Dist. 12.0
Study 45 Detection of Susceptibility Genes in ADHD ADHD Sandra Loo (new PI)

5R01MH058277-10

135 Data processing - final stages
Study 46 DM-STAT (data coordinating site for Studies 30, 31, 33, 34 & 41) Autism Dagher Released in AU Dist. 5.0 and 6.0
Study 47 A study of Autism (STAART) Autism Hollander 710 Withdrawn
Study 48 A study of Bipolar Disorder Bipolar Disorder McMahon, DePaulo, Gershon 186-188 642 Data received 2012; updated data received Sept 2016; still need fix pedigree
Study 49 Genetics of Bipolar Disorder in Latino Populations Bipolar Disorder Escamilla, Medoza, Paso, Paez, Jerez, Raventos, Nicolini, Ontiveros R01MH069856 190-197 2688 Released in BP Dist. 7.0
Study 50 Genetics of Autism Intermediate Phenotypes Autism Coon, Hepburn

R01MH069359

200-201 1711

129 in exome seq dbGap ARRA;

Released in AU Dist. 9.0
Study 51 A study of ADHD ADHD Todorov, Todd (deceased) 121 Due, in process
Study 52 Genetics of Early-Onset Major Depression (GenRED II) Depression DePaulo, Scheftner, Coryell, Weissman, Levinson, Lawson

R01MH060912

280-286 1902

450 in GenRED GWAS; 776 in GenRED II GWAS;

Released in DP Dist. 3.0
Study 53 A study of Autism Autism Sikich 162 Withdrawn
Study 54 A study of Autism Autism Hollander, Sigman, Sikich 721-723 Withdrawn
Study 55 Adolescents at High Risk for Familial Bipolar Disorder Bipolar Disorder Nurnberger, Kastelli, McInnis, Reich R01MH068009 750-753 374 Released in BP Dist. 8.0
Study 56 Clinical and Immunological Investigations of Subtypes of Autism Autism Swedo, Thurm, Amaral

1ZIAMH002868-09, NCT00298246, 1R01MH089626-01, 5U24MH081810-05, 1K99MH085099-01A1

 

163, 208 Released in AU Dist. 14.0
Study 57 A study of Autism Autism Wassink 166 Withdrawn
Study 58 Genetics of Brain Structure and Function Brain Function Blangero, Glahn

R01MH078143, R01MH078111

136 1300 Received data Aug 7, 2015, updates Aug 19, 2015, still need family id.
Study 59 High-Density Genome-Wide Association Study of Schizophrenia in Large Dutch Sample Schizophrenia Ophoff R01MH078075 100 331 Released in SZ Dist. 10.0
Study 60 A study of Autism Autism Piven

5P30HD003110-45, U10 DD000184-06/DD/NCBDD CDC HHS/United States, U50/CCU422345/PHS HHS/United States

 

167 275 Released in AU Dist. 14.0
Study 61 Molecular Genetic Studies of Human Anxiety Disorder Fear and Anxiety Weissman

P01MH60970

137 700 Released in Fear & Anxiety Dist. 1.0
Study 62 Molecular Genetic Studies of Human Anxiety Disorder Fear and Anxiety Fyer

P01MH60970

138 470 Released in Fear & Anxiety Dist. 1.0
Study 63 Interdisciplinary Studies of Insistence on Sameness in Autism Spectrum Disorders Autism Cook

P50HD55751

 

168 250

438 in exome seq dbGap UIC ACE;

Released in AU Dist. 13.0
Study 64 Center for Genomic and Phenomic Studies in Autism Autism Lajonchere, Amaral, Constantino, Roullet, Malow, Sohl, Manning, Murray

5U24MH081810

202-207, 229 1263

1 in exome seq dbGap ARRA;

Data processing - initial stages; Site 202 Released; Sites 203-207, 229 not released yet
Study 65 Trio Autism Simplex Collection (TASC) Autism Geschwind, Szatmari, Cook, Dawson, Poustka, Gallagher, Cuccaro, Vicente, McMahon, Sutcliffe, Buxbaum, Nurnberger 210-221 3374

1012 in exome seq dbGap ARRA; 1815 in dbGaP AGP;

Released in AU Dist. 10.0
Study 66 OCD Collaborative Genetics Association Study OCD Nestadt, Greenberg, Fyer, Pauls, McCracken

R01MH071507

240-244 3395

1539 in dbGap OCGAS;

Released in OCD Dist. 2.0
Study 67 Population Based Mapping of Schizophrenia Genes Schizophrenia Escamilla, Raventos

R01MH061884

129 1500 Due 4/1/2012
Study 68 Biological Prediction of Psychosis Susceptibility among Adolescent Cannabis Users Schizophrenia DeLisi

R01DA021576

18, 131 320 Released in SZ Dist. 14.0
Study 69 Biological and Information Processing Mechanisms Underlying Autism Autism Minshew

P50HD055748

209 Released in AU Dist. 13.0
Study 70 Consortium for Neuropsychiatric Phenomics RDoC Bilder

1UL1RR024911

182 2100 Samples and data released for sharing on an ongoing basis (12 mos. after receipt of a sample and the associated phenotype data); last sample received 1/20/2012
Study 71 Bipolar Endophenotypes in Population Isolates Bipolar Disorder Freimer, Macaya, Ospina-Duque R01MH075007 198-199 560 Released in BP Dist. 9.0
Study 72 Prediction of Relapse in Schizophrenia Schizophrenia Miller, Buckley, Goff, Lauriello, Manschreck, Mendelowitz, Wilson, Kopelowicz

3U01MH070010

261 230 Released in SZ Dist. 16.0
Study 73 Combining Medications to Enhance Depression Outcomes (CO-MED) Depression Trivedi, Nierenberg, Gaynes, Husain, Preskorn, Kerber, Young, Gilmer, McGrath, Friedman, Zisook, Mitchell, Davis, Lesser, Leuchter, Shelton, Kornstein 287 650 Released in DP Dist. 5.0
Study 74 Examination of Genetic and GxE Effects in the Family and Community Health Studies (FACHS) Depression Philibert, Beach

R01MH080898

133-134 800 Data received, processing and waiting for PI to clarify questions
Study 75 Lithium Use for Bipolar Disorder: A Randomized Controlled Effectiveness Trial (LiTMUS) Bipolar Disorder Nierenberg, Ostacher,Iosifescu, Thase, Ketter, Bowden, Calabrese, Friedman

Conducted under NIMH Bipolar Trials Network

189 193 Released in BP Dist. 11.0
Study 76 Genomic Psychiatry Cohort (GPC) Controls, Schizophrenia Pato, Pato, Knowles, Marder, Rapaport, Perkins, Buckley, Morley, Bromet, Lehrer, Malaspina, Escamilla, Nicolini

3R01MH085548-03S1

251,262-269, 271, 351-352 19657 Updates received 2016-12-02, in processing; Part 1 Released in SZ Dist. 13.0 and Controls Dist. 8.0
Study 77 International Cohort Collection for Bipolar Disorder Bipolar Disorder, Controls Smoller, Sklar, Pato, Knowles, Bromet, Rapaport, Buckley, Escamilla, Morley, Dewan, Lehrer, Marder, Perkins, Malaspina, Nicolini

R01MH085542

252, 270, 272-275, 304-312 8947 Updated data received 2016-12-02, in processing; Part 1 released in BP Dist. 10.0 and Controls Dist. 8.0
Study 78 Netherlands Twin Register Netherlands Twin Register Boomsma, de Geus R01D0042157-01A 169 8540 Released in NTR Dist. 1.0
Study 79 Genotypic and Phenotypic Factors in Autism Spectrum Disorders Autism Davis, Demmer, Caronna, Kunkel, Walsh, Frazier

R01MH085143, R01MH083565

222-227 1048

(lingwei note): 411 in exome seq dbGap ARRA;

29JUL2016(wbh): genomic data at NDAR under collection 2029, not for transfer to NRGR, target sequence data stays at NDAR, exome sequence goes to dbgap, according to David Obenshain of NDAR who cites agreement with Walsh lab; no gwas dataset

https://ndar.nih.gov/edit_collection.html?id=2029

 

NDAR Primary Deposit, study continued; first batch Released in AU Dist. 11.0
Study 80 Suicidal Behavior in Mood Disorders: Genes and Intermediate Phenotypes Suicide Mann, Turecki, Rujescu

R01MH082041

288-290 1100 Released in Suicide Dist. 1.0
Study 81 Predictors and Mechanisms of Conversion to Psychosis (NAPLS) Addington, Walker, Seidman, Mathalon, Cannon, Cadenhead, Perkins, Woods, Cornblatt

R01MH082004

291-298 960 Samples and data released for sharing 12 mos. after receipt; last sample received 7/24/2014; due 7/24/2015
Study 82 Expanding Rapid Ascertainment Networks of Schizophrenia Families in Taiwan Schizophrenia Tsuang M., Hwu

R01MH085560

183 12000 Released in SZ Dist. 15.0
Study 83 Incomplete Response in Late Life Depression: Getting to Remission Depression Reynolds, Lenze, Mulsant 277-279 500 Released in DP Dist. 6.0
Study 84 Predictors of Antidepressant Treatment Response: The Emory CIDAR; Predictors of Treatment Response, Relaps, and Recurrence in Major Depression Depression Mayberg, Craighead

P50MH077083, R01MH080880

276 500 Data received; In processing
Study 85 Language and Risk in Schizophrenia Schizophrenia DeLisi

R21MH083205

260 90 Released in SZ Dist. 14.0
Study 86 Autism-Spectrum Disorder Genetics Autism Haines

5P01NS026630-20, 5R01NS036768-10, 5R01MH080647-15

 

230 1500 Released in AU Dist. 14.0
Study 87 Emory-MSSM-GSK-NIMH Collaborative Mood and Anxiety Disorders Initiative PTSD Mayberg, Dunlo, Iofescu, Mathew, Neyland

U19MH069056

299-300, 313-314 154 Released in PTSD Dist. 1.0 (11/8/2016)
Study 88 Depression Susceptibility Genes and Networks: Expression, eQTL and GWAS Analysis Depression Levinson, Weissman, Potash RC2MH089916 621 1000 937 in GenREDII GWAS,922 in RNAseq Released in DP Dist. 4.0
Study 89 Identification of Characteristics Associated with Symptom Remission in Autism Autism Black 231 180 Due 8/1/2013
Study 90 A genome-wide association study of Schizophrenia in Ireland Schizophrenia Riley, Corvin, O'Neill

R01MH083094

301-302 1500

Received GWAS data on portable hard drive on 7-22-2015

Updated clinical data for both GWAS and NIMH new collected data received 12/18/2015
Study 91 Whole-genome sequencing for rare highly penetrant gene variants in schizophrenia Schizophrenia Goldstein

RC2MH089915

258-259 110

162 in dbGaP phs000682

 

Released in SZ Dist. 11.0
Study 92 Family-Based Genome-Wide Methylation Scan in Neurocognition and Schizophrenia iPSC, Schizophrenia Gur, Nimgaonkar

RC2MH089973

RC2MH089859

320-323 200 Released in iPSC Dist. 6.0
Study 93 Identifying Intermediate Phenotypes for Compulsive Hoarding OCD Mathews

R21MH087748

245 135 Released in Compulsive Hoarding Dist. 1.0 under OCD group
Study 94 Common and rare variant genetic screens for clozopine-induced agranulocytosis (CIAC) Schizophrenia Sullivan, Lieberman, Malhotra, Kennedy

R01MH080403

324-326 1000

22 in SZ DS31_1; 282 in SZ DS31_2;282 in SZ DS31_3;

Released in SZ Dist. 17.0
Study 95 Abnormal Sterols in ASD and NIMH HGI Repository Expansion (4000) Autism Tierney, Porter, Arnold

RC2MH090027

232-234 400 Due 11/30/2013
Study 96 Olanzapine Versus Placebo in Outpatients with Anorexia Nervosa Anorexia Nervosa Attia, Steinglass, Guarda, Marcus, Kaplan

R01MH085921, NCT01170117

395-399 160 Data will be deposited within 3 months from end of data preparation
Study 97 Studies of Autistic Patients: Gene Networks and Clinical Subtypes Autism Rennert, Swedo, Thurm, Raygado 235 300 Due 12/31/2013
Study 98 The Effects of Estradiol on Genetic Risk for Disordered Eating during Puberty Anorexia Nervosa Klump

R01MH092377

246 700 Data received 2014-03-06, updates needed; 6 mos. after last subject's sample has been received by repository
Study 99 Brain-Behavior and Genetic Studies of the 22q11DS 22q11.2 Deletion Syndrome Gur, Emanuel

U01MH087626

247-248 1000 Due 10/1/2016
Study 100 A Longitudinal Imaging Study of Infants at Risk for Autism Autism Piven, Schultz, Botteron, Dagar

R01HD055741

236-239 700 NDAR primary deposit; Data will be submitted to NDAR around December 2016
Study 101 Pharmacogenomics of Mood Stabilizer Response in Bipolar Disorder Bipolar Disorder Kelsoe, Nievergelt, Calabrese, Nurnberger, McInnis, Gershon, Potash, Zandi, Berrettini, Lohoff, Coryell, Alda, Odegaard

U01MH092758

420-429 700 Clinical trials. Due 6/30/2015
Study 102 Genomic Studies of Bipolar Disorder in a Large Cohort from the Netherlands Bipolar Disorder Ophoff, Daalman

R01MH090553

430-431 2500 9th RFD email sent 4/5/2017; Due 3/31/2015
Study 103 Efficacy and Tolerability of Riluzole in Treatment-Resistant Depression Depression Sanacora, Mathew, Fava, Zarate

5R01MH085055, 5R01MH085054, 5R01MH085050

622-625 275 Due 12/31/2014
Study 104 Comparison of Long-Acting Injectable Medications for Schizophrenia (ACLAIMS) Schizophrenia Stroup, Lawrence, Byerly, Caroff, D'Souza, Khan, Lamberti, Lieberman, McEvoy, Miller, Steinbook, Jarskog, Buckley, Desouza, D'Mello, Grabowski, Hicks, Hoblyn, Konicki, Tran, Wilson, Millet

R01MH081107

327-347 360 Released in SZ Dist. 16.0
Study 105 Establishing Moderators/Biosignatures of Antidepressant Response- Clinical Care (EMBARC) Depression Trivedi, Weissman, McGrath, Parsey, McInnis, Fava

U01MH092221, U01MH092250

626-629 400 Will be released 6 mos. after last subject's sample has been received by repository; last sample received 4/7/2016
Study 106 Collaborative genomic studies of Tourette Disorder Tourette Syndrome State, Heiman, Brown, Gilbert, Hoskstra, Visser, Mir, Morer, Roessner, Ludolph, Munchau, Heyman, Hedderly, von Plessen, Koh, Kim, Song, Choen, Song, Hong, Kim, Kim, Kuperman, Grice, Zinner, Coffey, Leventhal

R01MH092290, R01MH092291, R01MH092292, R01MH092293, R01MH092513, R01MH092516, R01MH092520, R01MH092289, U24MH068457

600-609 (active sites); 610-620 (reserved) 1548 Released in TS Dist. 1.0 (sites 600-609)
Study 107 RAISE - Early Treatment Program (ETP) Genetics Schizophrenia Kane, et al.

Contract No. HHSN-271-2009-00019C

350 (all 32 sites using site # 350; have subsite #s) 400 data received, processing not started
Study 108 Sustaining Remission of Psychotic Depression Depression Meyers (retired), Rothschild, Whyte, Flint

5U01MH062518, 5U01MH062624, 5U01MH062565, 4U01MH062446

630-633 400 data received, processing not started
Study 109 Discovery Science of Human Brain Function Across the Lifespan Brain Function Milham R01MH094639 303 1000 Released in Brain Function Dist. 1.0
Study 110 D-Cycloserine Augmentation of CBT for Pediatric OCD OCD Geller, Storch

R01MH093402, R01MH093381

249-250 150 Data received through QC 8/10/2016, clinical trials data will be from NIMH; Will be released 6 mos. after last subject's sample has been received by repository
Study 111 Biomarkers for Psychosis in Velo-cardio-facial Syndrome 22q11.2 Deletion Syndrome Kates

R01MH064824

394 60 Released in 22q11.2DS Dist. 1.0
Study 112 The Genetics of Autism: Epilepsy as a Biomarker Autism Devinsky (724-725), Schultz (740) 724-725, 740 1200 Released in AU Dist. 14.0
Study 113 Identifying Biomarkers for Post-Partum Depression in African-American Women Depression Sullivan, Rubinow

R01MH095992

634 2000 Will be released 6 mos. after last subject's sample has been received by repository; last sample received 6/60/2016; due 12/30/2016
Study 114 Mapping the Human Connectome: Structure, Function, and Heritability Brain Function Van Essen

U54MH091657

400 1800 need to contact humanconnectiome.org;8th RFD email sent 3/7/2017; last sample received 10/1/2015; due 4/1/2016
Study 115 Exploring the Neuronal Phenotype of Autism Spectrum Disorders Using Induced Pluri iPSC, Phelan-McDermid Syndrome Hallmayer, Dolmetsch

R33MH087898

726 & 734 150 Released in iPSC Dist. 1.0 (2/19/2014) & PMS Dist. 1.0 (4/15/2014)
Study 116 Cellular and genetic correlates of increased head size in autism spectrum disorder iPSC Vaccarino

R33MH087879

727 40 Released in iPSC Dist. 2.0
Study 117 Autism iPSCs for Studying Function and Dysfunction in Human Neural Development iPSC Loring

R33MH087925

728 8 Released in iPSC Dist. 1.0
Study 118 Next Generation Gene Discovery in Familial Autism Autism Brkanac

R01MH092367

729 60 NDAR primary deposit: requesting access
Study 119 Attaining and Maintaining Wellness in OCD OCD Simpson, Foa

R01MH045436, R01MH045404

401-402 140 Will be released 6 mos. after last subject's sample has been received by repository; last sample received 11/23/2016; due 5/31/2017
Study 120 RDoC Constructs: Neural Substrates, Heritability, and Relation to Psychopathology RDoC Zald, Lahey

R01MH098098

500 400 Released in RDoC Dist. 1.0
Study 121 Depression (RAPID LFMS) Depression Fava, Papakostas, Madhukar, Iosifescu, Sanacora, Rapaport, Shelton

HHSN271201100006I; Double-Blind, Proof-of-Concept (PIC) Trial of Low Field Magnetic Stimulation (LFMS) Augmentation of Antidepressant Therapy in Treatment-Resistant Depression (TRD)

754-759 90 Will be released 6 mos. after last subject's sample has been received by repository; last sample received 4/15/2016; due 10/15/2016
Study 122 Characterization of a Mendelian Form of Psychosis in a Population Isolate Schizophrenia Raventos, Glahn, Almasy

R56MH097940

319 200 Phenotypic data received through QC. Watiting for documentations and clarifications from PI
Study 123 Acute Psychotherapy for Bipolar II Depression Bipolar Disorder Swartz R01MH084831 432 38 Released in BP Dist. 10.0
Study 124 Multi-pronged genetic studies of schizophrenia in an inbred population Schizophrenia Mansour, Nimgaonkar

R01MH093246

349 760 Will be released 6 mos. after last subject's sample has been received by repository; last sample received 6/14/2016; due 12/14/2016
Study 125 Analysis of Glutamatergic Neurons Derived from Patient Specific iPS Cells iPSC Lachman, Rapoport

R33MH087840

392-393 31 Released in iPSC Dist. 1.0
Study 126 Autism (ACE Network) Autism Constantino, Klin, Molholm

R01MH100027

712, 718-720 600 NDAR Primary Deposit; Will be released 6 mos. after last subject's sample has been received by repository
Study 127 Target Identification and Validation for Negative Symptoms and Social Cognition in Schizophrenia: A Translational Study iPSC Hahn

Donation (funded by Pfizer)

717 50 Will be released 6 mos. after last subject's sample has been received by repository; last sample received 4/1/2013; due 10/1/2013
Study 128 A Comprehensive Approach To Identification of Autism Susceptibility Genes Autism Lajonchere, Schultz, Johnson, Reynolds, Butter

R01MH081754

713-716 196 NDAR primary deposit: requesting access; Will be released 6 mos. after last subject's sample has been received by repository
Study 129 Anorexia Nervosa Genetics Initiative (ANGI Project) Anorexia Nervosa Bulik (UNC), Martin (Australian site) Note: Australian site will send samples in 2 batches (at the end of years 2 and 4)

Donation (funded by Klarman Foundation)

403-404 2000 Will be released 6 mos. after last subject's sample has been received by repository
Study 130 Genomics-Guided Characterization of iPS Cells from Common Mental Illnesses iPSC Haggarty, Perlis

R33MH087896, R21MH093958

433-434 27 Released in iPSC Dist. 7.0
Study 131 Chemical genomic approaches to neurobiology of DISC1 iPSC Tsai, Perlis, Cohen

R01MH091115

317-318 40 Will be released 6 mos. after last subject's sample has been received by repository; last sample received 6/9/2015; due 12/9/2015
Study 132 NIMH DIRP Protocol 03-M-0035 Screening, Evaluation, Diagnosis, Treatment Optimization and Follow-Up for Childhood Onset Psychiatric Disorders iPSC Rapoport

1ZIAMH002581

499, 502 270 site 499 Released in iPSC Dist. 3.0; still need site 502.
Study 133 Biomarker Discovery in Anorexia Nervosa II Anorexia Nervosa Bulik, Bardone-Cone R01MH095860 405 420 Due 12 mos. after last subject's sample has been received by repository
Study 134 Genetic Study of Trichotillomania OCD Scharf, Keuthen

There is no grant number for this study. Funded by the Trichotillomania Learning Center (TLC).

508, 788, 790 938 Site 508 released in Trichotillomania Distribution 1.0 under OCD group; Sites 788 & 790 will be released no later than 6/16/2020
Study 135 Multimodal Developmental Neurogenetics of Females with ASD Autism Pelphrey, Nelson, Bookheimer, Webb R01MH100028 470-473 312 Will be released 6 mos. after last subject's sample has been received by repository
Study 136 Integrative Molecular and Phenotype Analysis of 22q11.2 Deletion Syndrome iPSC, 22q11.2 Deletion Syndrome Hallmayer

R01MH100900

355 180 iPSC lines-2 mos. after publication of relevant studies but no later than 2/1/2017; LCLs and fibroblasts (samples submitted by 8/1/2015)-will be released on 10/1/2015; LCLs and fibroblasts (all remaining samples, which should be submitted by 2/1/2017)-will be released on 4/1/2017
Study 137 Genomics of Schizophrenia in the South African Xhosa Controls, Schizophrenia Stein U01MH096754-01A1 356 2200 Will be released 6 mos. after last subject's sample has been received by repository
Study 138 Identification of rare variants of OCD OCD Nedstadt

R01MH097993-01A1

406 160 Will be released 6 mos. after last subject's sample has been received by repository but no later than 6/30/2018
Study 139 Addition of OCD to the Genomic Psychiatry Cohort OCD M. Pato, Knowles, Nurmi, Nicolini, Richter

R01MH103657

407, 417, 783, 787, 805 5000 Will be released 6 mos. after last subject's sample has been received by repository but no later than 2/1/2020
Study 140 Genome Sequencing in Extended Bipolar Pedigrees Bipolar Disorder, Controls Fremier, Jaramillo, Macaya

3R01MH095454-02S1

435-436 2000 Needs to resolve ids in blood file before submitting to Auto-QC. Will be released 6 mos. after last subject's sample has been received by repository but no later than 11/30/2015
Study 141 Genetic Analysis of High-Risk Utah Suicide Pedigrees Suicide Coon R01MH099134 315 5100 Will be released 6 mos. after last subject's sample has been received by repository but no later than 11/30/2018
Study 142 Psychosis and Affective Research Domains and Intermediate Phenotypes (PARDIP) RDoC Tamminga, Keshavan, Pearlson

R01MH096913-01A1

496-498 405 Due 12 mos. after last subject's sample has been received by repository but no later than 10/1/2017
Study 143 Modeling Anorexia Nervosa with Human Pluripotent Stem Cells iPSC Muotri

R21MH093954-02

408 30 Released in iPSC Dist. 4.0
Study 144 Modeling Autism with Human Pluripotent Cells iPSC Muotri

1DP2OD006495

738 81 Released in iPSC Dist. 4.0
Study 145 Genetically Engineered Human Pluripotent Stem Cells as a Platform to Define the B iPSC Jaenisch R01MH4610 737 5 No later than 9/30/2019
Study 146 Induced Neuronal Cells: A Novel Approach to Study Neuropsychiatric Diseases Autism, iPSC Wernig, Südhof

R01MH092931

741 12 Released no later than 10/31/2015
Study 147 Longitudinal Family/Molecular Genetic Study to Validate Research Domain Criteria RDoC Glatt, Faraone

1R01MH101519-01A1

501 2800 Will be released 6 mos. after the project end date, 3/31/2019
Study 148 Identifying Regulatory Mutations that Influence Neuropsychiatric Disease Schizophrenia Goldstein, Pulver, Levy

U01MH105670-01

357-359 340 Due 3 mos. after last subject's sample has been received by repository but no later than 11/30/2018
Study 149 Rapidly-Acting Treatments for Treatment-Resistant Depression (RAPID) Depression Fava, Cusin, Iosifescu, Trivedi, Mathew, DeBattista, Sanacora

HHSN271201100006I (contract)

760-765 100 Will be released 6 mos. after last subject's sample has been received by repository but no later than 5/15/2016
Study 150 A Study of Schizophrenia Schizophrenia Sullivan, Josiassen

There is no grant number associated with this study

354 500 phenotype data received, in processing
Study 151 Predictors and Mechanisms of Conversion to Psychosis Cannon, Bearden, Walker, Perkins, Cadenhead, Addington, Cornblatt, Woods, Mathalon, Seidman

2R01MH081902-06A1

486-494 540 Will be released at time of publication or within 3 mos. of the project's end (2/1/2020), whichever comes first
Study 152 Control and Reward Circuits as Targets for Repetitive Thoughts and Behaviors Controls, OCD Marsh, Simpson

R01MH104648-01

409 80 Will be released 6 mos. after the end of the grant, 2/28/2019
Study 153 Double-Blind, Placebo-Controlled, Proof-of-Concept (POC) Trial of LY2456302, a Kappa-Selective Opioid Receptor Antagonist, Augmentation of Antidepressant Therapy in Treatment-Resistant Depression (TRD) Depression Fava, Carpenter, Morrison, Zajecka, Macaluso, Shelton

HHSN271201100006I

635-639 90 Will be released 6 mos. after last subject’s sample has been received by repository but no later than 2/15/2017
Study 154 FAST MAS KOR Phase 2a RDoC Krystal, Sanacora, Lisanby, Calabrese, Mathew, Nurnberger, Goodman

HHSN271201100006I

410-415 90 Will be released 6 mos. after last subject's sample has been received by the repository but no later than 6/28/2017
Study 155 Gene Networks Influencing Psychotic Dysconnectivity in African Americans Schizophrenia Glahn

R01MH106324-01

360 750 Will be released 6 mos. after last subject’s sample has been received by repository but no later than 2/28/2020
Study 156 Transferred from Coriell Collection Bipolar Disorder, Schizophrenia DeLisi, Gershon Site 735 (BP); Site 736 (SZ) 2500 Data received, waiting on PI resolve issues, 2016-3-2 contacted with excel files, 2016-5-23 send follow-up emails
Study 157 Neuroinflammation and Aggression (RDoC) RDoC Coccaro

1R01MH104673-01A1

503 150 Will be released 3 mos. after last subject’s sample has been received by repository but no later than 10/1/2019
Study 158 Modeling schizophrenia using iPSC neurons iPSC, Schizophrenia Brennand, Gage

No grant number associated with this study. Supported by private funds

361 14 Released in iPSC Dist. 5.0
Study 159 A chimeric brain model to study human neurological diseases iPSC Muotri

1R21MH107771-01

742 6 Will be released at publication but no later than project end (2015-08-31), whichever comes first
Study 160 Contrasting causal microRNAs in forebrain and midbrain COS hiPSC neural cells iPSC Brennand

5R01MH101454-02

504 50 Released in iPSC Dist. 6.0
Study 161 iPSC Derived Human Cortical Interneurons as Developmental Model of Schizophrenia iPSC Sangmi Chung

1R01MH107884-01

362-363, 807 7 Will be released 3 mos. after submissions are complete but no later than 2/28/2021
Study 162 Bipolar-Schizophrenia Network for Intermediate Phenotypes 2 (BSNIP2) Schizophrenia Tamminga, Clementz, Gershon, Keshavan, Pearlson

2R01MH077851-05A1, 1R01MH103366-01A1, 1R01MH103368-01A1, 2R01MH078113-05A1, 2R01MH077945-05A1

364-368 3600 Will be released no later than 12 mos. after the end of the project, 3/31/2015
Study 163 Neuropsychiatric Genome-Scale and RDoC Individualized Domains (N-GRID) iPSC Isaac Kohane, Roy Perlis

5P50MH106933

416 400 Released in iPSC Dist. 7.0
Study 164 The Autism Biomarkers Consortium for Clinical Trials (ABC-CT) Autism McPartland, Charwarska, Nelson, Dawson, Jeste, Bernier

1U19MH108206-01

474-478 200 Will be released 3 mos. after the end of the project period, 9/30/2019
Study 165 Neural development of human induced pluripotent stem cells from schizophrenia patients iPSC Hongjun Song, Russell Margolis

R21/R33MH087874

369 13 Will be released no later than 4/30/2016
Study 166 Juvenile Onset Schizophrenia iPSCs iPSC Paul Tesar

R21/R33MH087877

370 23 Samples and data can be released immediately
Study 167 Biomarker Assessment of Pomaglumetad on Glutamate Targets: Proof of Clinical Mechanism of Action (POCM) Controls Jeffrey Lieberman, Daniel Javitt, Donald Goff, Stephen Marder, Adrienne Lahti

HHSN271201200007I, HHSN27100003, NCT02919774

793-796 81 Clinical trials;Will be released to the public no later than 10/28/2017
Study 168 Mapping the Human Connectome During Typical Aging Brain Function David Van Essen, Melissa Terpstra, Susan Bookheimer, David Salat

1U01AG052564

797-800 1500 Will be released to the public no later than 11/30/2020
Study 169 Genomics of Postpartum Depression Depression Patrick Sullivan

There is no grant number associated with this study

769 25000 Will be released to the public no later than 6/30/2020
Study 170 Cognitive-Affective Psychosis Proneness Risk and Protective Factors in 22q11.2DS 22q11.2 Deletion Syndrome Tony J. Simon

1R01MH107108-1

770 150 Will be released to the public no later than 1/31/2021
Study 171 Genetic Contributions of Negative Valence Systems to Internalizing Pathways RDoC Roxann Roberson-Nay

5R01MH101518

771 800 Will be released to the public no later than 1/31/2018
Study 172 A Clinical Study to Establish a Metabolic Biomarker-Based Test to Diagnose Autism Spectrum Disorder in Early Childhood Autism Robert Burrier (PI), David Amaral, Daniel Coury, Melmed Raun, Kevin Sanders, Richard Frye, Logan Wink, Ann Neumeyer

1R44MH107124-01

772-777, 784, 786 1500 Will be released to the public no later than 1/31/2019
Study 173 Collaboration on Preclinical Autism Cellular Assays, Biosignatures, and Network Analyses (COPACABANA) iPSC Eugene W. Yeo/Lawrence Goldstein

1U19MH107367-01

778 19 Will be released to the public no later than 2/26/2020
Study 174 The Role of Dysmyelination in Cognitive Impairment of Psychotic Disorders Mariana Lazar

1R01MH108962-01

779 210 Will be released to the public no later than 5/30/2021
Study 175 Neurobiology of Autism with Macrocephaly Autism Flora Vaccarino

R01MH109648

780 120 Will be released to the public no later than 10/30/2021
Study 176 iPSC Phenotype, Mitochondrial Haplotype and Psychosis in 22q11 Deletion Syndrome iPSC Stewart A. Anderson

R01MH110185-01

781 9 Will be released to the public no later than 8/31/2019
Study 177 Mitochondrial Dysfunction in Schizophrenia iPSC Marquis Philip Vawter

2R01MH085801-06A1

782 12 Will be released to the public no later than 6/30/2021
Study 178 Human Connectome Project for Early Psychosis Brain Function Martha Elizabeth Shenton, Alan Breier

U01MH109977

791-792 400 Will be released to the public no later than 8/29/2020
Study 179 Ultra High Field Strength MRI and MRS Study of Bipolar Disorder in Adolescents Bipolar Disorder Hilary Patricia Blumberg

1R21MH108940-01A1

789 52 Will be released to the public no later than 12/30/2018
Study 180 Mapping the Human Connectome During Typical Development Brain Function David Van Essen, Deanna Barch, Leah Somerville, Susan Bookheimer, Kathleen Thomas

1U01MH109589

801-804 1500 Will be released to the public no later than 10/30/2020
Study 181 Development of new therapeutic targets for patients with bipolar disorder who are resistant to conventional psychotropic medications using induced Pluripotent Stem Cells (iPSC) iPSC Fred H. Gage

There is no grant number associated with this study

806 80 Will be released to the public no later than 11/30/2020
Study 182 Systematic Functional Interpretation of Regulatory Variants in Schizophrenia iPSC Jubao Duan, Peter Penzes

R01MH106575

808-809 99 Will be released to the public no later than 9/30/2021
Study 183 Multimodal Analysis of High-Risk Psychosis Mutations in Induced Neuronal Cells iPSC Douglas Levinson, Thomas Sudhof, Marius Wernig

U19MH104172

810-811 100 Will be released to the public no later than 1/31/2020
Study 184 iPSC-based platform development for major psychiatric disorder modeling and discovery iPSC Fred H. Gage, Hongjun Song

U19MH106434

812-813 123 Will be released to the public no later than 11/30/2021
Study 185 Alzheimer's Disease Connectome Project Brain Function Shi-Jiang Li, Barbara Bendlin

UF1AG051216

814-815 600 Will be released to the public no later than 10/30/2020
Study 186 Dissecting functional roles of schizophrenia risk gene ZNF804a in neural development iPSC Yingwei Mao

R21MH108983

816-817 9 Will be released to the public no later than 10/30/2018
Study 187 Healthy Brain Network Brain Function Michael Milham, Jasmine Escalera

Not associated with an active grant

818 6500 Will be released to the public no later than 3/30/2023
Rutgers University Rutgers University USC Information Sciences Institute Washington University in St.Louis National Institute of Mental Health