Summary of Data and BioSamples
Summary Information about available Data and BioSamples.
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22q11.2 Deletion Syndrome

Distribution 1.0 for the 22q11.2 Deletion Syndrome data is now available with data from NIMH Study 111 (PI: Kates). This new collection contains a total of 64 individual cases; all 64 subjects have cell_line and 58 have plasma available.

Distribution 1.1: added the variable dist for distribution number.

Distribution 1.2: standardized variables in distribution file.

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Attention-Deficit Hyperactivity Disorder (ADHD)

Distribution 1.0 for the Attention-deficit Hyperactivity Disorder Genetics Initiative contains 5,734 records in 1,331 families from Study 25, including dummy pedigree connector records and counting singletons as a family. N=4954 subjects have blood samples.

Distribution 1.1: added the variable dist for distribution number.

Distribution 1.2: conforms the dataset to the standard NRGR schema.

Distribution 1.3: conforms the dataset to the standard NRGR schema column order; no new data.

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Alzheimer's Disease

Distribution 3.0 for the Alzheimer's Disease data is now available. This new collection includes data from Study 17 (CATIE-AD). Study 17 added 185 subjects bringing the total to 2,682 with 1,596 having DNA. No plasma available in this collection.

Distribution 3.1: added the variable dist for distribution number.

Distribution 3.2: standardized variables in distribution file.

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Anorexia Nervosa
Distribution 2.1 for the Anorexia Nervosa data is now available. This new collection contains 2,891 records in 849 families from Study 24 and Study 98, including dummy pedigree connector records. N=1569 subjects have DNA. Dist. 2.0 adds n=860 new subjects from Study 98 (PI: Klump), n=364 with DNA.
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Autism

Distribution 14.0 for the Autism data is now available with new data from NIMH Study 56 (PI: Thurm), Study 60 (PI: Piven), Study 86 (PI: Haines), and Study 112 (Devinsky). This collection contains 5,285 families and 21,466 individuals of which 18,822 have DNA cell lines. New in this collection are a total of 495 families (1,840 individuals, 1,646 with DNA).

Distribution 14.1: added the variable dist for distribution number.

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Bipolar Disorder

Distribution 12.0 for the Bipolar Disorder Data is now available. This new distribution includes data from Study 48 Part 1 (PIs: McMahon, DePaulo, Gershon; Application # NA_00038551) and Study 140 (PIs: Freimer, Jaramillo, Macaya, Raventos; 3R01MH095454-02S1. Study 48 Part 1 added 701 subjects and Study 140 added 349 subjects bringing the total to 25,736 subjects with 4,277 having plasma available.

Distribution 12.1: replaced Study 77 (5,042 subjects) with updated version; total 26,285 subjects, 19,579 cell lines, and 4,374 had plasma available.

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Brain Function

Distribution 2.0 for the Brain Function data is now available. This distribution includes data from Study 58 (PIs: John Blangero, David Glahn; 5R01MH078111, R01MH078143, R01MH083824).

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CommonMind Consortium
The CommonMind Consortium Knowledge Portal Release 1.2 data is now available.
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Controls

Distribution 8.0 for the Controls data is now available. This distribution includes data from Study 76 (PIs: Carlos Pato, et al.; 3R01MH085548-03S1) and Study 77 (PIs: Jordan Smoller, Pamela Sklar, et al.; R01MH085542).

Distribution 8.1: standardized variables in distribution file.

Distribution 8.2: added the variable dist for distribution number.

Distribution 8.3: standardized variables in distribution file.

Distribution 8.4: fixes consent value to GRU and replaces Study 76 with updated version.

Distribution 8.5: replaced Study 77 with updated version and excluded DNG subjects.

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Depression

Distribution 7.0 for Depression adds data from Study 84 (PATR-Emory CIDAR; PIs: Mayberg, Craighead) and Study 108 (SRPD; PIs: Meyers, Alexopoulos, Rothschild, Whyte, Flint). Study 84 added 460 individuals (231 have DNA cell lines and 198 with plasma available. Study 108 added 177 individuals (177 have DNA cell lines and 130 with plasma available. This distribution contains 12,291 individuals in 6,327 families. 8,039 individuals have DNA cell lines and 883 individuals have plasma available. There is no pedigree information available for Study 84 and Study 108.

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Fear & Anxiety

Distribution 1.0 for Fear & Anxiety includes data from Study 61/Site 137 (PIs: Weissman, et al.) and Study 62/Site 138 (PIs: Fyer, et al.). This new collection contains 320 cases from Study 61 (no plasma) and 60 controls from Study 61 plus 197 subjects (no dx) from Study 62 (no plasma).

Distribution 1.1: added the variable dist for distribution number.

Distribution 1.2: standardized variables in distribution file and Study 61 and 62 controls file.

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iPSC
Distribution 10.0 for the iPSC data is now available with new data from NIMH Study 132 (PI: Rapoport) and NIMH Study 165 (PIs: Song, Margolis). In Study 132, there are 44 individuals from 17 families, 0 iPSCs, and 44 fibroblasts. In Study 165, there are 4 individuals from 2 families, 9 iPSCs, and 0 fibroblasts.
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Netherlands Twin Register (NTR)

Distribution 2.0 for the Netherlands Twin Register data is now available. This new collection includes 9,131 subjects with Rutgers IDs and their families (number of families=3656), total 11,989 subjects.

Distribution 2.1: standardized variables and added the variable dist for distribution number.

Distribution 2.2: standardized variables in distribution file.

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Obsessive-Compulsive Disorder (OCD) Compulsive Hoarding

Distribution 1.0 for the Trichotillomania data is now available with the data from Study 134; site 508 (PI: Kuethen). This includes 513 individuals from 295 families and 419 indivduals have cell lines. Distribution 1.1 standardizes variables. Distribution 1.2 added the variable dist for distribution number. Distribution 1.3 standardizes variables.

Distribution 1.0 for the Compulsive Hoarding data is now available with data from Study 93; site 245 (PI: Mathews). This includes 102 individuals from 60 case families and 41 individual controls. Distribution 1.1 standardized variables. Distribution 1.2 added the variable dist for distribution number. Distribution 1.3 standardized variables in distribution file and Study 93 controls file.

Distribution 2.4 for the Obsessive-Compulsive Disorder (OCD) data is now available with data from Study 66 (sites 240-244). There are 1,156 new families and 3,921 new individuals for a total of 1,483 families and 5,634 individuals. Distribution 2.5: added the variable dist for distribution number. Distribution 2.6: standardized variables in distribution file.

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Phelan-McDermid Syndrome

Distribution 1.0 includes data from Study 115; Sites 726 & 734 (PIs: Hallmayer, Dolmetsch; Phelan McDermid Foundation). There are 165 individuals from 55 families. There are 55 probands.

Distribution 1.1: standardized variables in Dist. 1.0 and adds auxiliary files.

Distribution 1.2: added the variable dist for distribution number.

Distribution 1.3: standardized variables in distribution file.

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Post-traumatic Stress Disorder (PTSD)

Post-traumatic Stress Disorder (PTSD) Dist. 1.0 includes data from Study 87; Sites 299, 300, 313 & 314 (PIs: Mayberg, et al.). There are a total of 108 subjects from 108 families (108 subjects with cell lines; 107 have plasma available). Clinical data is currently unavailable.

Distribution 1.1: added the variable dist for distribution number.

Distribution 1.2: standardized variables in distribution file.

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PsychENCODE Consortium
The PsychENCODE Consortium Knowledge Portal data release for August 2016 is now available.
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Research Domain Criteria (RDoC)

Distribution 1.0 for the RDoC Data is now available with data from NIMH Study 120 (PIs: Zald, Lahey; Tennessee Twin Study). This collection contains 396 individuals in RDocDB and 414 dummy parents for a total of 820 individuals from 212 families; 396 with cell lines and 256 have plasma available.

Distribution 1.1: standardized variables in distribution file.

10/23/2017: added the pedigree drawings for Study 120.

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Schizophrenia

Distribution 20.0 for the Schizophrenia Data is now available with new data from NIMH Study 92 (PIs: Gur, Nimgaonkar), Study 122 (PIs: Raventós, Glahn, Almasy), and updated Study 76 (PIs: Pato, et al.). This new collection contains a total of 54,787 individuals in 22,254 families (37,766 individuals have DNA cell lines available; 17,429 individuals have plasma available). New in this distribution are:

Study 92 - 32 individuals from 32 families (32 subjects with cell lines and 29 subjects with plasma).

Study 122 - 325 individuals from one family (215 subjects with cell lines and 209 subjects with plasma).

Updated Study 76 - 10,069 individuals from 8,940 familie (9,784 subjects with cell lines and 5,671 subjects with plasma). Note: 9,276 subjects in Dist. 19.0 were replaced by 10,069 subjects in Dist. 20.0.

Distribution 20.1: fixed 15 subjects whose dx_study='PNOS'. The dx_nimh should be NSPECT, not OTHER.

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Suicide

Distribution 1.0 for the Suicide Data is now available with new data from NIMH Study 80 (PIs: Mann, Turecki, Rujesca). This collection contains 181 subjects including 159 controls and 22 probands, 3 have plasma.

Distribution 1.1: reordered and renamed variables in distribution file.

Distribution 1.2: added the variable dist for distribution number.

Distribution 1.3: standardized variables in distribution file.

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Tourette Syndrome

Distribution 1.0 for the Tourette Syndrome Data is now available with new data from NIMH Study 106/Sites 600-609 (PIs: State, Tischfield, Heiman, et al.). This collection contains a total of 2,981 subjects from 780 families (2,646 subjects have DNA cell lines available; 2,208 subjects have plasma available).

Distribution 1.1: corrected dx from ChronicTic to TDChronicTic.

Distribution 1.2: corrected several genders.

Distribution 1.3: added the variable dist for distribution number and fixed cell_id for 4 subjects.

Distribution 1.4: updates in May 2017 and standardized variables.

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