Autism

NOTE: The distribution refers to a collection of studies organized by disorder or theme (see FAQ). It is important to note that not all individuals in the distribution have DNA available.

Given the major public health implications of identifying genes responsible for severe neuropsychiatric disorders, the National Institute of Mental Health (NIMH) has funded a Human Genetics Initiative. The goal of this Initiative is to establish a national resource of clinical data and biomaterials that are collected from individuals with autism, schizophrenia, bipolar I disorder, depression, obsessive-compulsive disorder, and other mental disorders. The NIMH Autism Genetics Initiative is supported by the Office of Human Genetics & Genomic Resources in NIMH's Division of Neuroscience and Basic Behavioral Science (DNBBS). Starting in 2001, data and biomaterials (cell lines and DNA samples) will be available to qualified investigators who study the genetics of autism, and may be accessed by following a set of instructions.

Dist. 13.0/September 2015

List of Studies

Available for Download

Study	Title	Target Sample Size	Status
Study 4	Collaborative Linkage Study of Autism	665	Released
Study 10	Collaborative Linkage Study in Autism	4	Released
Study 14	Molecular Genetics of Infantile Autism	563	Released
Study 21	AGRE; A Genomewide Search for Autism Susceptibility Loci	3908	Released in AU Dist. 7.0
Study 30	A study of Autism	50	Released in AU Dist. 5.0
Study 31	A study of Autism	79	Released in AU Dist. 5.0
Study 32	A study of Autism	483	Released in AU Dist. 5.0
Study 33	Longitudinal Study of Language and Theory of Mind in Autism	210	Released in AU Dist. 5.0
Study 34	Neurobiology and Genetics of Autism	214	Released in AU Dist. 5.0
Study 35	Molecular and Genetic Epidemiology of Autism	1220	Released in AU Dist. 8.0
Study 36	A study of Autism	310	Released in AU Dist. 5.0
Study 37	RUPP-PI	133	Released in AU Dist. 5.0
Study 39	A study of Autism		Released in AU Dist. 13.0
Study 41	The Development of the Siblings of Children with Autism: A Longitudinal Study	438	Site 702 still collecting samples, project end date is 31-MAY-2017; Sites 700-705, 707 were released in AU Dist 6.0
Study 44	Genetic Analysis of 15q11-q13 in Autism		Released in AU Dist. 12.0
Study 46	DM-STAT (data coordinating site for Studies 30, 31, 33, 34 & 41)		Released in AU Dist. 5.0 and 6.0
Study 50	Genetics of Autism Intermediate Phenotypes	1711	Released in AU Dist. 9.0
Study 63	Interdisciplinary Studies of Insistence on Sameness in Autism Spectrum Disorders	250	Released in AU Dist. 13.0
Study 64	Center for Genomic and Phenomic Studies in Autism	1263	Data processing - initial stages; Site 202 Released; Sites 203-207, 229 not released yet
Study 65	Trio Autism Simplex Collection (TASC)	3374	Released in AU Dist. 10.0
Study 69	Biological and Information Processing Mechanisms Underlying Autism		Released in AU Dist. 13.0
Study 79	Genotypic and Phenotypic Factors in Autism Spectrum Disorders	1048	NDAR Primary Deposit, study continued; first batch Released in AU Dist. 11.0

In Progress*

Study	Title	Target Sample Size	Status
Study 41	The Development of the Siblings of Children with Autism: A Longitudinal Study	438	Site 702 still collecting samples, project end date is 31-MAY-2017; Sites 700-705, 707 were released in AU Dist 6.0
Study 56	Clinical and Immunological Investigations of Subtypes of Autism		Data processing complete - will distribute soon
Study 60	A study of Autism	275	Data processing complete - will distribute soon
Study 64	Center for Genomic and Phenomic Studies in Autism	1263	Data processing - initial stages; Site 202 Released; Sites 203-207, 229 not released yet
Study 79	Genotypic and Phenotypic Factors in Autism Spectrum Disorders	1048	NDAR Primary Deposit, study continued; first batch Released in AU Dist. 11.0
Study 86	Autism-Spectrum Disorder Genetics	1500	Data processing complete - will distribute soon
Study 89	Identification of Characteristics Associated with Symptom Remission in Autism	180	Waiting for data
Study 95	Abnormal Sterols in ASD and NIMH HGI Repository Expansion (4000)	400	Waiting for data
Study 97	Studies of Autistic Patients: Gene Networks and Clinical Subtypes	300	Waiting for data
Study 100	A Longitudinal Imaging Study of Infants at Risk for Autism	700	NDAR primary deposit; Data will be submitted to NDAR around December 2016
Study 112	The Genetics of Autism: Epilepsy as a Biomarker	1200	Data processing complete - will distribute soon
Study 118	Next Generation Gene Discovery in Familial Autism	60	NDAR primary deposit: requesting access
Study 126	Autism (ACE Network)	600	NDAR Primary Deposit; Will be released 6 mos. after last subject's sample has been received by repository
Study 128	A Comprehensive Approach To Identification of Autism Susceptibility Genes	196	NDAR primary deposit: requesting access; Will be released 6 mos. after last subject's sample has been received by repository
Study 135	Multimodal Developmental Neurogenetics of Females with ASD	312	Will be released 6 mos. after last subject's sample has been received by repository
Study 146	Induced Neuronal Cells: A Novel Approach to Study Neuropsychiatric Diseases	12	RFD 7/25/2016; No later than 10/31/2015
Study 164	The Autism Biomarkers Consortium for Clinical Trials (ABC-CT)	200	Will be released 3 mos. after the end of the project period, 9/30/2019
Study 172	A Clinical Study to Establish a Metabolic Biomarker-Based Test to Diagnose Autism Spectrum Disorder in Early Childhood	1500	Will be released to the public no later than 1/31/2019
Study 175	Neurobiology of Autism with Macrocephaly	120	Will be released to the public no later than 10/30/2021

*Studies in progress includes those available for download for which some future action is required